| Combined thallium-201 myocardial with technetium-99m-HMPAO brain SPECT: myocardial ischemia induced by acetazolamide in severe coronary artery disease. | |
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MedLine Citation:
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PMID: 9529283 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Since the perioperative mortality of coronary artery bypass surgery is high in patients with cerebrovascular disease, it is crucial to assess a cerebrovascular risk before operation. Acetazolamide (ACZ) was applied to brain SPECT to evaluate the vascular reserve, and ACZ stress brain imaging was useful for predicting perioperative cerebrovascular events. We performed 201Tl myocardial and 99mTc-hexamethyl-propyleneamine oxime (HMPAO) brain SPECT with ACZ stress simultaneously to a patient with severe coronary artery disease and experienced the abnormality of 201Tl myocardial imaging with ACZ, as did that with dipyridamole. Technetium-99m-HMPAO brain SPECT showed no defect. Brain SPECT with ACZ demonstrated the region of poor coronary vascular reserve, which suggested myocardial ischemia induced by ACZ in a patient with severe coronary artery disease. |
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Authors:
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Y Shimotsu; K Hayashida; Y Hirose; N Kume; T Nishimura |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of nuclear medicine : official publication, Society of Nuclear Medicine Volume: 39 ISSN: 0161-5505 ISO Abbreviation: J. Nucl. Med. Publication Date: 1998 Mar |
Date Detail:
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Created Date: 1998-04-13 Completed Date: 1998-04-13 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0217410 Medline TA: J Nucl Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 408-10 Citation Subset: IM |
Affiliation:
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Department of Radiology, National Cardiovascular Center, Suita, Osaka, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acetazolamide
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diagnostic use*,
pharmacology Aged Brain / radionuclide imaging* Cerebrovascular Circulation / drug effects Cerebrovascular Disorders / radionuclide imaging Coronary Artery Bypass Coronary Circulation / drug effects Coronary Disease / radionuclide imaging* Female Heart / radionuclide imaging* Humans Myocardial Ischemia / chemically induced*, radionuclide imaging Preoperative Care Radiopharmaceuticals / diagnostic use* Technetium Tc 99m Exametazime / diagnostic use* Thallium Radioisotopes / diagnostic use Tomography, Emission-Computed, Single-Photon* Vasodilator Agents / diagnostic use*, pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Radiopharmaceuticals; 0/Thallium Radioisotopes; 0/Vasodilator Agents; 100504-35-6/Technetium Tc 99m Exametazime; 59-66-5/Acetazolamide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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