| Combined pulmonary fibrosis and emphysema syndrome: a review. | |
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MedLine Citation:
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PMID: 22215830 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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There is increasing clinical, radiologic, and pathologic recognition of the coexistence of emphysema and pulmonary fibrosis in the same patient, resulting in a clinical syndrome known as combined pulmonary fibrosis and emphysema (CPFE) that is characterized by dyspnea, upper-lobe emphysema, lower-lobe fibrosis, and abnormalities of gas exchange. This syndrome frequently is complicated by pulmonary hypertension, acute lung injury, and lung cancer. The CPFE syndrome typically occurs in male smokers, and the mortality associated with this condition, especially if pulmonary hypertension is present, is significant. In this review, we explore the current state of the literature and discuss etiologic factors and clinical characteristics of the CPFE syndrome. |
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Authors:
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Matthew D Jankowich; Sharon I S Rounds |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Chest Volume: 141 ISSN: 1931-3543 ISO Abbreviation: Chest Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-01-04 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0231335 Medline TA: Chest Country: United States |
Other Details:
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Languages: eng Pagination: 222-31 Citation Subset: AIM; IM |
Affiliation:
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Providence VA Medical Center, Office 158L, 830 Chalkstone Ave, Providence, RI 02908. Matthew_jankowich@brown.edu. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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