Document Detail


Combined phlebotomy and ursodeoxycholic acid treatment in the patients with chronic hepatitis C.
MedLine Citation:
PMID:  10838036     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
As an option to interferon, either iron removal by phlebotomy or ursodeoxycholic acid administration has been recommended for patients with chronic hepatitis C. Some patients, however, show only partial responses to such monotherapy. In the present study, we investigated the effects of a combination of phlebotomy and ursodeoxycholic acid in the patients who did not show normalization of serum alanine aminotransferase levels by either phlebotomy or ursodeoxycholic acid monotherapy. The combination of these therapies in any order additively improved the biochemical parameter to the upper normal range. There were no statistically significant differences between the results of the two combination treatments. The combination treatment was also effective in decreasing serum alpha fetoprotein levels.
Authors:
Wakusawa; Ikeda; Takikawa; Hayashi; Yano; Yoshioka
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Hepatology research : the official journal of the Japan Society of Hepatology     Volume:  18     ISSN:  -     ISO Abbreviation:  Hepatol. Res.     Publication Date:  2000 Jul 
Date Detail:
Created Date:  2000-06-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9711801     Medline TA:  Hepatol Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  54-62     Citation Subset:  -    
Affiliation:
Department of Medicine, Faculty of Pharmaceutical Sciences, Hokuriku University, Ho-3 Kanagawa-machi, 920-1181, Kanazawa, Japan
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