Document Detail

Combined occurrence of von Willebrand's disease and factor XIII deficiency: a case report.
MedLine Citation:
PMID:  15022915     Owner:  NLM     Status:  MEDLINE    
We report the case of a three year old female child with combined occurrence of von Willebrand's disease and factor XIII deficiency, an extremely rare combination. The patient presented with prolonged bleeding following cuts and wounds. Clot solubility test using 5M urea was positive. Platelet aggregation using ristocetin was reduced, which corrected on adding normal plasma. Aggregation with other agonists was normal. We discuss the clinico- hematological profile of the case. Only one such case has been reported in literature in the past to the best of our knowledge.
Vineeta Vijay Batra; Renu Saxena; Lalit Mohan Sharma; Rajesh Kashyap; Ved Prakash Chaudhry
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Indian journal of pathology & microbiology     Volume:  46     ISSN:  0377-4929     ISO Abbreviation:  Indian J Pathol Microbiol     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2004-03-16     Completed Date:  2004-04-14     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  7605904     Medline TA:  Indian J Pathol Microbiol     Country:  India    
Other Details:
Languages:  eng     Pagination:  217-9     Citation Subset:  IM    
Department of Hematology, All India Institute of Medical Sciences, New Delhi.
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MeSH Terms
Child, Preschool
Factor XIII Deficiency / blood,  complications*
von Willebrand Diseases / blood,  complications*

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