Document Detail

Combined iliac angioplasty and infrainguinal revascularization surgery are effective in diabetic patients with multilevel arterial disease.
MedLine Citation:
PMID:  11221947     Owner:  NLM     Status:  MEDLINE    
The success of percutaneous transluminal angioplasty (PTA) in the treatment of common and external iliac atherosclerotic lesions has been established for the general population. However, several studies have suggested that the presence of diabetes may reduce the effectiveness of iliac angioplasty, particularly in the setting of limb-threatening ischemia requiring concomitant lower extremity revascularization. This study compared the results of iliac artery PTA performed in conjunction with infrainguinal bypass for limb-threatening ischemia for diabetic (DM) and nondiabetic (non-DM) patients. Between 1991 and 2000, 159 PTA were performed in 126 patients (DM = 99/79%, non-DM = 27/21%) in conjunction with subsequent infrainguinal bypass for limb-threatening ischemia (gangrene = 42%, ulcer = 36%, rest pain = 22%). These patients were followed prospectively using a computerized vascular registry. Stents were placed in 34 (21.4%) cases for suboptimal angioplasty results. In this study the combined use of standard surgical and endoluminal modalities for the treatment of multilevel arterial occlusive disease resulted in excellent cumulative patency and limb salvage rates. The presence of diabetes did not alter these favorable results. Multimodal vascular therapy may be used effectively in diabetic patients with limb-threatening ischemia due to multiple levels of arterial occlusion.
P L Faries; D Brophy; F W LoGerfo; C M Akbari; D R Campbell; L D Spence; S C Hook; F B Pomposelli
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of vascular surgery     Volume:  15     ISSN:  0890-5096     ISO Abbreviation:  Ann Vasc Surg     Publication Date:  2001 Jan 
Date Detail:
Created Date:  2001-02-26     Completed Date:  2001-05-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8703941     Medline TA:  Ann Vasc Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  67-72     Citation Subset:  IM    
Department of Surgery, Mount Sinai School of Medicine, New York, NY, USA.
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MeSH Terms
Angioplasty, Balloon* / adverse effects
Arteriosclerosis / complications,  therapy*
Diabetic Angiopathies / complications,  therapy*
Iliac Aneurysm*
Ischemia / complications,  surgery*
Leg / blood supply*
Life Tables
Middle Aged
Vascular Patency
Vascular Surgical Procedures* / adverse effects

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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