Document Detail

Combined epidural and general anaesthesia versus general anaesthesia for abdominal aortic surgery: a prospective randomised trial.
MedLine Citation:
PMID:  8122735     Owner:  NLM     Status:  MEDLINE    
Fifty patients undergoing elective abdominal aortic surgery were randomised to receive either combined epidural and general anaesthesia and postoperative epidural analgesia (CEGA) or general anaesthesia and postoperative intravenous morphine infusion (GA). Prospective data was collected in order to compare the two groups. This included intraoperative cardiovascular changes and postoperative complications. The use of intraoperative vasopressors was significantly higher in the CEGA group (P < 0.01) but the use of intravenous glyceryl trinitrate was significantly lower (P < 0.01). There was no significant difference between groups in regard to blood loss, volume replacement or in the number of patients requiring postoperative ventilation. Two patients in the CEGA group died postoperatively compared to one in the GA group (not significant). There was no significant difference between groups in the total number or type of postoperative complications. Combining epidural anaesthesia with general anaesthesia altered intraoperative cardiovascular management but did not affect postoperative outcome.
M J Davies; B S Silbert; P J Mooney; R H Dysart; A C Meads
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Anaesthesia and intensive care     Volume:  21     ISSN:  0310-057X     ISO Abbreviation:  Anaesth Intensive Care     Publication Date:  1993 Dec 
Date Detail:
Created Date:  1994-04-04     Completed Date:  1994-04-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0342017     Medline TA:  Anaesth Intensive Care     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  790-4     Citation Subset:  IM    
Department of Anaesthesia, St Vincent's Hospital, Melbourne, Victoria.
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MeSH Terms
Analgesia / methods*
Analgesia, Epidural
Anesthesia, Epidural*
Anesthesia, General*
Aorta, Abdominal / surgery
Aortic Diseases / surgery*
Bupivacaine / administration & dosage
Ephedrine / therapeutic use
Follow-Up Studies
Infusions, Intravenous
Intraoperative Care
Metaraminol / therapeutic use
Morphine / administration & dosage
Nitroglycerin / therapeutic use
Pain, Postoperative / prevention & control
Postoperative Complications
Prospective Studies
Reg. No./Substance:
2180-92-9/Bupivacaine; 299-42-3/Ephedrine; 54-49-9/Metaraminol; 55-63-0/Nitroglycerin; 57-27-2/Morphine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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