Document Detail


Combined epidermal-connective tissue nevus of proteoglycan (a type of mucinous nevus): a case report and literature review.
MedLine Citation:
PMID:  19519615     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Mucinous nevus is a rare entity with only 11 cases reported previously. It may be divided into two histopathologic types: connective tissue nevus of the proteoglycan (CTNP) and combined epidermal-CTNP. We describe a boy with asymptomatic grouped brown papuloplaques on the lower back since birth. A diagnosis of mucinous nevus of the combined epidermal-CTNP type was made after a biopsy. We vaporized two lesions with carbon dioxide laser, and the wounds healed satisfactorily. We present a literature review indicating a striking preponderance of male patients (M : F = 5 : 1) for mucinous nevus. In half of the cases, mucinous nevus did not appear until childhood, adolescence or early adulthood. The predominantly affected site was the trunk. Half of the cases can be assigned to the CTNP type and the other half to the combined epidermal-CTNP type. We propose that carbon dioxide laser vaporization may be a treatment option for mucinous nevus of the combined epidermal-CTNP type with multiple lesions but not for the CTNP type.
Authors:
Ching-Chi Chi; Shu-Hui Wang; Paul Y Lin
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of cutaneous pathology     Volume:  36     ISSN:  1600-0560     ISO Abbreviation:  J. Cutan. Pathol.     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-06-12     Completed Date:  2009-08-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0425124     Medline TA:  J Cutan Pathol     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  808-11     Citation Subset:  IM    
Copyright Information:
(c) 2009 John Wiley & Sons A/S.
Affiliation:
Department of Dermatology, Chang Gung Memorial Hospital, Chiayi, Taiwan.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Biopsy
Epidermis / pathology
Female
Humans
Laser Therapy
Male
Nevus / classification*,  pathology*,  therapy*
Proteoglycans*
Skin Neoplasms / classification*,  pathology*,  therapy*
Chemical
Reg. No./Substance:
0/Proteoglycans

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