| Combined endoscopic and radiologic intervention to treat esophageal varices. | |
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MedLine Citation:
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PMID: 12143259 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND/AIMS: In patients with esophageal varices, we investigated the impact on long-term outcome of combining interventional radiologic procedures with endoscopic therapy. METHODOLOGY: Of 133 patients with esophageal varices, 86 were treated with endoscopic therapy alone and 47 underwent endoscopic therapy in addition to interventional radiologic procedures. End-points considered during 5-years of follow-up included recurrent bleeding and retreatment. RESULTS: Bleeding rates were 24.4% in the endoscopy group and 25.4% in the combined therapy group. Retreatment rates at 1, 3, and 5 years for the endoscopy group versus the combined therapy group were 40.7% versus 30.3%, 72.0% versus 67.5%, and 88.2% versus 80.5%, respectively, representing no significant difference between two groups. However, cumulative retreatment rates in Child's class C cases were significantly lower in the combined therapy group than in the endoscopy group (P = 0.025). Patients who had combined therapy which included all embolizing techniques showed significantly lower retreatment rates than patients treated with endoscopy alone (P = 0.05). CONCLUSIONS: In combination, interventional radiologic and endoscopic therapies are highly effective and can improve long-term outcome in patients with esophageal varices, especially those with poor liver function and those who undergo embolization by all techniques. |
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Authors:
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N Taniai; M Onda; T Tajiri; H Yoshida; Y Mamada |
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Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article |
Journal Detail:
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Title: Hepato-gastroenterology Volume: 49 ISSN: 0172-6390 ISO Abbreviation: Hepatogastroenterology Publication Date: 2002 Jul-Aug |
Date Detail:
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Created Date: 2002-07-29 Completed Date: 2003-02-13 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8007849 Medline TA: Hepatogastroenterology Country: Greece |
Other Details:
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Languages: eng Pagination: 984-8 Citation Subset: IM |
Affiliation:
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First Department of Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyou-ku, Tokyo 113-8603, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Angiography Combined Modality Therapy Embolization, Therapeutic / methods* Esophageal and Gastric Varices / radiography, therapy* Esophagoscopy / methods* Female Gastrointestinal Hemorrhage / radiography, therapy* Humans Ligation / methods Male Middle Aged Portography Sclerotherapy / methods* Spleen / blood supply Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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