| Combined elective percutaneous coronary intervention and transapical transcatheter aortic valve implantation. | |
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MedLine Citation:
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PMID: 22232234 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There is no established strategy of how and when to treat coronary artery disease (CAD) in patients referred for transcatheter aortic valve implantation (TAVI). Simultaneous, single-stage treatment of both pathologies is a possible solution. We report our initial results of simultaneously performed transapical TAVI and elective percutaneous coronary interventions (PCI) in high-risk patients with severe aortic valve stenosis. Between April 2008 and July 2011, a total of 419 patients underwent transapical TAVI. Combined elective PCI and TAVI were performed in 46 (11%) patients. Only the most significant coronary lesion or lesions were treated. Technical success of the combined approach was 100%. The mean count of implanted stents per patient was 1.6 ± 1.0 (range, 1-5 stents). The 30-day mortality rates in the PCI and TAVI group was 4.3%. Survival at 12, 24 and 36 months of the PCI and TAVI group 87.1 ± 5.5, 69.7 ± 10.3 and 69.7 ± 10.3%, respectively. The results showed that the single-stage approach with combined elective PCI and TAVI is feasible and safe. It has become our primary choice for treatment of high-risk patients with severe aortic valve stenosis and CAD. |
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Authors:
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Miralem Pasic; Stephan Dreysse; Axel Unbehaun; Semih Buz; Thorsten Drews; Christoph Klein; Giuseppe D'Ancona; Roland Hetzer |
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Publication Detail:
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Type: Journal Article Date: 2012-01-09 |
Journal Detail:
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Title: Interactive cardiovascular and thoracic surgery Volume: 14 ISSN: 1569-9285 ISO Abbreviation: Interact Cardiovasc Thorac Surg Publication Date: 2012 Apr |
Date Detail:
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Created Date: 2012-03-22 Completed Date: 2012-07-24 Revised Date: 2013-04-01 |
Medline Journal Info:
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Nlm Unique ID: 101158399 Medline TA: Interact Cardiovasc Thorac Surg Country: England |
Other Details:
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Languages: eng Pagination: 463-8 Citation Subset: IM |
Affiliation:
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German Heart Center, Berlin, Germany. pasic@dhzb.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Angioplasty, Balloon, Coronary* / adverse effects, instrumentation, mortality Aortic Valve Stenosis / complications, diagnosis, mortality, therapy* Cardiac Catheterization* / adverse effects, mortality Coronary Angiography Coronary Stenosis / complications, diagnosis, mortality, therapy* Feasibility Studies Female Germany Heart Valve Prosthesis Implantation / adverse effects, methods*, mortality Humans Kaplan-Meier Estimate Male Severity of Illness Index Stents Time Factors Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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