Document Detail

Combined elective percutaneous coronary intervention and transapical transcatheter aortic valve implantation.
MedLine Citation:
PMID:  22232234     Owner:  NLM     Status:  MEDLINE    
There is no established strategy of how and when to treat coronary artery disease (CAD) in patients referred for transcatheter aortic valve implantation (TAVI). Simultaneous, single-stage treatment of both pathologies is a possible solution. We report our initial results of simultaneously performed transapical TAVI and elective percutaneous coronary interventions (PCI) in high-risk patients with severe aortic valve stenosis. Between April 2008 and July 2011, a total of 419 patients underwent transapical TAVI. Combined elective PCI and TAVI were performed in 46 (11%) patients. Only the most significant coronary lesion or lesions were treated. Technical success of the combined approach was 100%. The mean count of implanted stents per patient was 1.6 ± 1.0 (range, 1-5 stents). The 30-day mortality rates in the PCI and TAVI group was 4.3%. Survival at 12, 24 and 36 months of the PCI and TAVI group 87.1 ± 5.5, 69.7 ± 10.3 and 69.7 ± 10.3%, respectively. The results showed that the single-stage approach with combined elective PCI and TAVI is feasible and safe. It has become our primary choice for treatment of high-risk patients with severe aortic valve stenosis and CAD.
Miralem Pasic; Stephan Dreysse; Axel Unbehaun; Semih Buz; Thorsten Drews; Christoph Klein; Giuseppe D'Ancona; Roland Hetzer
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Publication Detail:
Type:  Journal Article     Date:  2012-01-09
Journal Detail:
Title:  Interactive cardiovascular and thoracic surgery     Volume:  14     ISSN:  1569-9285     ISO Abbreviation:  Interact Cardiovasc Thorac Surg     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-03-22     Completed Date:  2012-07-24     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  101158399     Medline TA:  Interact Cardiovasc Thorac Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  463-8     Citation Subset:  IM    
German Heart Center, Berlin, Germany.
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MeSH Terms
Aged, 80 and over
Angioplasty, Balloon, Coronary* / adverse effects,  instrumentation,  mortality
Aortic Valve Stenosis / complications,  diagnosis,  mortality,  therapy*
Cardiac Catheterization* / adverse effects,  mortality
Coronary Angiography
Coronary Stenosis / complications,  diagnosis,  mortality,  therapy*
Feasibility Studies
Heart Valve Prosthesis Implantation / adverse effects,  methods*,  mortality
Kaplan-Meier Estimate
Severity of Illness Index
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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