Document Detail

Combined effect of ozone and sulfuric acid on pulmonary function in man.
MedLine Citation:
PMID:  3565273     Owner:  NLM     Status:  MEDLINE    
A potential effect of the combination of ozone and sulfuric acid mist (H2SO4) on respiratory function has been postulated for humans simultaneously exposed to these two pollutants. Nine young men were exposed to 0.25 ppm ozone (O3), 1200-1600 micrograms/m3 sulfuric acid aerosol (H2SO4), and a combination of O3 and H2SO4. During the 2-hr exposures, the subjects exercised (ventilation = 30 L/min) three times for 20 min each. Air temperature was 35 degrees C and relative humidity 83%. Pulmonary function changes after exposure to ozone alone were not expected and were not demonstrated. If a reaction between the combination of O3 and H2SO4 and pulmonary function occurred, pulmonary function responses may have been anticipated following the combination exposure, but no significant changes were seen. It was concluded that the combination of ozone and sulfuric acid aerosol at levels in excess of Threshold Limit Values (TLV) levels do not cause pulmonary dysfunction.
S M Horvath; L J Folinsbee; J F Bedi
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  American Industrial Hygiene Association journal     Volume:  48     ISSN:  0002-8894     ISO Abbreviation:  Am Ind Hyg Assoc J     Publication Date:  1987 Feb 
Date Detail:
Created Date:  1987-05-06     Completed Date:  1987-05-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0371160     Medline TA:  Am Ind Hyg Assoc J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  94-8     Citation Subset:  IM    
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MeSH Terms
Drug Combinations
Ozone / pharmacology*
Respiration / drug effects*
Sulfuric Acids / pharmacology*
Reg. No./Substance:
0/Aerosols; 0/Drug Combinations; 0/Sulfuric Acids; 10028-15-6/Ozone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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