| Combined continuous monitoring of systemic and cerebral oxygen metabolism after cardiac arrest. | |
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MedLine Citation:
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PMID: 7667548 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cerebral oxygenation was assessed in 8 patients in cardiac arrest during the 24 h after resuscitation, by continuous fiber-optic monitoring of jugular bulb venous oxygen saturation (SjO2), in conjunction with continuous monitoring of mixed venous oxygen saturation (SvO2). Three patients survived and 5 died. SjO2 and SvO2 patterns were compared between surviving and non-surviving patients with regard to their prognostic and therapeutic implications. The mean SjO2 of the survivors (67%) was significantly lower than that of the non-survivors (80%) (P < 0.001), whereas the corresponding SvO2 value was higher in the survivor group (74%) than in the non-survivor group (64%) (P < 0.001). Three of the non-survivors died of brain death within 5 days after resuscitation, and then the others died of respiratory or cardiovascular failure without recovering from deep coma. The high SjO2 of the non-survivors suggests that an inability of damaged neurons to use oxygen may be an indicator of poor neurological outcome in resuscitated patients after cardiac arrest. When SjO2 was < 45%, Sv-O2 was extremely low, reflecting cardiovascular failure after resuscitation. SjO2 may thus serve to warn of deterioration in cardiopulmonary function and serve as a predictor of outcome in cardiac arrest survivors. |
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Authors:
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A Takasu; K Yagi; S Ishihara; Y Okada |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Resuscitation Volume: 29 ISSN: 0300-9572 ISO Abbreviation: Resuscitation Publication Date: 1995 Jun |
Date Detail:
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Created Date: 1995-10-12 Completed Date: 1995-10-12 Revised Date: 2009-08-25 |
Medline Journal Info:
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Nlm Unique ID: 0332173 Medline TA: Resuscitation Country: IRELAND |
Other Details:
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Languages: eng Pagination: 189-94 Citation Subset: IM |
Affiliation:
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Department of Traumatology and Critical Care Medicine, National Defense Medical College, Saitama, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Brain
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metabolism* Brain Death / metabolism Cardiac Output Case-Control Studies Female Heart Arrest / metabolism*, mortality, therapy Humans Jugular Veins Male Middle Aged Monitoring, Physiologic / methods Oximetry / methods Oxygen / blood* Oxygen Consumption / physiology* Prognosis Resuscitation |
| Chemical | |
Reg. No./Substance:
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7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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