Document Detail

Combined approach for internal carotid artery stenosis and cardiovascular disease in septuagenarians--a comparative study.
MedLine Citation:
PMID:  10647827     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The best surgical approach for concomitant carotid artery and cardiac disease remains controversial. Many studies proved the safety and efficiency of simultaneous surgery. We aimed to demonstrate the same benefits for patients > or = 70 years. METHODS: We retrospectively evaluated 205 patients simultaneously operated upon between 1988 and 1998. Group A comprised patients < 70 years (n = 110), group B > or = 70 years, (n = 95). Risk factors, neurologic and cardiac history, angiographic findings, operative data, morbidity and mortality (30-day-postoperatively) were analysed. The mean age was 62 years in group A and 75 years in group B. All patients with symptomatic carotid artery disease, stenosis > 70% or ulcerative carotid disease had simultaneous surgery. Always, the carotid artery was addressed first. RESULTS: Patients in group B had a higher prevalence of peripheral vascular disease (P = 0.0005), renal insufficiency (P = 0.0011) and COPD (P = 0.03). Urgent operation was indicated in 19% of group A patients vs. 37% in group B. In group A 70% were asymptomatic regarding the carotid vs. 48% in group B. Left ventricular dysfunction was present in 45% (group A) and 58% (group B). In the present study 4% in group A and 7% in group B suffered a perioperative myocardial infarction. Pathologic changes of the contralateral carotid were found in 42 vs. 57% (A vs. B). Mortality due to cardiac causes was 1 and 5%, respectively. The combination of persistent neurologic deficit and neurologic death occurred in 3% in group A (n = 3) and 5% in group B (n = 5). Postoperative neuro-cognitive dysfunction was more common in group B (35 vs. 16%; P = 0.01). CONCLUSIONS: The incidence of persistent neurologic deficits and neurologic mortality in patients > or = 70 years is acceptable, and low in patients < 70 years. Preoperative risk factors are increasing with age and are related to the higher mortality in elderly patients. Due to our results we will conclude that the combined approach for carotid stenosis and cardiovascular disease is the method of choice in this high-risk population.
T Busch; H Sirbu; I Aleksic; S Kazmaier; M Friedrich; W Buhre; H Dalichau
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery     Volume:  16     ISSN:  1010-7940     ISO Abbreviation:  Eur J Cardiothorac Surg     Publication Date:  1999 Dec 
Date Detail:
Created Date:  2000-02-09     Completed Date:  2000-02-09     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8804069     Medline TA:  Eur J Cardiothorac Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  602-6     Citation Subset:  IM    
Department of Thoracic and Cardiovascular Surgery, Klinik und Poliklinik für Thorax-, Herz- und Gefässchirurgie, Georg-August-University, Goettingen, Germany.
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MeSH Terms
Aged, 80 and over
Cardiac Surgical Procedures*
Cardiopulmonary Bypass
Carotid Stenosis / complications,  diagnosis,  mortality,  surgery*
Endarterectomy, Carotid*
Feasibility Studies
Heart Catheterization
Heart Diseases / complications,  diagnosis,  mortality,  surgery*
Middle Aged
Retrospective Studies
Survival Rate
Tomography, X-Ray Computed
Treatment Outcome
Ultrasonography, Doppler, Transcranial

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