| Combined Doppler index to track instantaneous changes in left ventricular filling pressure. | |
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MedLine Citation:
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PMID: 16128376 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The ratio of early transmitral pulsed Doppler velocity (E) to colour M-mode Doppler flow propagation velocity (Vp) has been reported to be a good predictor of pulmonary capillary wedge pressure (PCWP) and left ventricular end-diastolic pressure (LVEDP). It is unknown whether E/Vp can be used to reflect the instantaneous haemodynamic change after drug intervention. METHODS AND RESULTS: The study population was composed of 19 patients who underwent elective cardiac catheterization for suspected coronary artery disease. Mean PCWP (mPCWP) obtained from right heart catheterization and LVEDP from a micromanometer-tipped catheter were compared with echocardiographic data before and 5 minutes after sublingual application of nitroglycerin (NTG) 0.6 mg. By stepwise multiple linear regression analysis, we found a positive correlation between mPCWP and E/Vp (beta, = 0.687, p = 0.001) and LVEDP and E/Vp (beta, = 0.718, p = 0.001). After NTG intake, the change in ENp was significantly correlated with the changes in mPCWP and LVEDP (r = 0.574, p = 0.010; r = 0.627, p = 0.004, respectively). CONCLUSIONS: In addition to being a useful predictor of mPCWP and LVEDP, the index, E/Vp, can be used to track the instantaneous changes in mPCWP and LVEDRP. |
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Authors:
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Ho-Ming Su; Tsung-Hsien Lin; Wen-Chol Voon; Wen-Ter Lai; Sheng-Hsiung Sheu |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta cardiologica Volume: 60 ISSN: 0001-5385 ISO Abbreviation: Acta Cardiol Publication Date: 2005 Aug |
Date Detail:
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Created Date: 2005-08-30 Completed Date: 2006-02-16 Revised Date: 2009-06-11 |
Medline Journal Info:
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Nlm Unique ID: 0370570 Medline TA: Acta Cardiol Country: Belgium |
Other Details:
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Languages: eng Pagination: 421-5 Citation Subset: IM |
Affiliation:
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Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Blood Flow Velocity Catheterization, Swan-Ganz Coronary Artery Disease / diagnosis, physiopathology*, ultrasonography Echocardiography, Doppler, Color / methods* Female Humans Linear Models Male Middle Aged Pulmonary Wedge Pressure / physiology* Ventricular Function, Left / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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