Document Detail


Combined Churg-Strauss Syndrome and Allergic Bronchopulmonary Aspergillosis-case report and review of the literature.
MedLine Citation:
PMID:  22325470     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A rare case of combined Churg-Strauss syndrome (CSS) and allergic bronchopulmonary aspergillosis(ABPA) was presented. A 41-year-old woman was diagnosed with CSS based upon asthma, eosinophilia (23%), chest radiographic findings, paranasal sinusitis, peripheral neuropathy and positive p-ANCA. The diagnosis of ABPA was established on the pathological findings of allegic mucin impaction and fungal hyphae on lung biopsy. It was further proved by positive serum IgE and IgG antibodies specific to afumigatus. The clinical investigation features were reviewed in the patients with combined CSS and ABPA. All patients had the time sequence of the development of CSS after ABPA uniformly, suggesting immunopathogenesis involving with the emergence of CSS . The role of lung biopsy in the diagnosis of the condition was emphasized.
Authors:
Shaohua Ren
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-10
Journal Detail:
Title:  The clinical respiratory journal     Volume:  -     ISSN:  1752-699X     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-2-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101315570     Medline TA:  Clin Respir J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 Blackwell Publishing Ltd.
Affiliation:
From the Department of Respiratory Medicine, Lishui Central Hospital, Zhejiang Province 323000, P.R. China(Dr Ren).
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