Document Detail

The combined association of psychological distress and socioeconomic status with all-cause mortality: a national cohort study.
MedLine Citation:
PMID:  23212347     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Psychological distress and low socioeconomic status (SES) are recognized risk factors for mortality. The aim of this study was to test whether lower SES amplifies the effect of psychological distress on all-cause mortality.
METHODS: We selected 66 518 participants from the Health Survey for England who were 35 years or older, free of cancer and cardiovascular disease at baseline, and living in private households in England from 1994 to 2004. Selection used stratified random sampling, and participants were linked prospectively to mortality records from the Office of National Statistics (mean follow-up, 8.2 years). Psychological distress was measured using the 12-item General Health Questionnaire, and SES was indexed by occupational class.
RESULTS: The crude incidence rate of death was 14.49 (95% CI, 14.17-14.81) per 1000 person-years. After adjustment for age and sex, psychological distress and low SES category were associated with increased mortality rates. In a stratified analysis, the association of psychological distress with mortality differed with SES (likelihood ratio test-adjusted P < .001), with the strongest associations being observed in the lowest SES categories.
CONCLUSIONS: The detrimental effect of psychological distress on mortality is amplified by low SES category. People in higher SES categories have lower mortality rates even when they report high levels of psychological distress.
Antonio Ivan Lazzarino; Mark Hamer; Emmanuel Stamatakis; Andrew Steptoe
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  JAMA internal medicine     Volume:  173     ISSN:  2168-6114     ISO Abbreviation:  JAMA Intern Med     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-02-20     Completed Date:  2013-03-14     Revised Date:  2013-12-09    
Medline Journal Info:
Nlm Unique ID:  101589534     Medline TA:  JAMA Intern Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  22-7     Citation Subset:  AIM; IM    
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MeSH Terms
Aged, 80 and over
England / epidemiology
Health Surveys / statistics & numerical data
Middle Aged
Proportional Hazards Models
Random Allocation
Risk Factors
Social Class*
Stress, Psychological* / epidemiology,  mortality
Grant Support
RG/10/005/28296//British Heart Foundation
Comment In:
JAMA Intern Med. 2013 Jan 14;173(1):27-8   [PMID:  23212409 ]
Evid Based Ment Health. 2013 Nov;16(4):118   [PMID:  23897973 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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