Document Detail


Combinatorial domain swaps provide insights into the rules of fungal polyketide synthase programming and the rational synthesis of non-native aromatic products.
MedLine Citation:
PMID:  23283670     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Authors:
Anna L Vagstad; Adam G Newman; Philip A Storm; Katherine Belecki; Jason M Crawford; Craig A Townsend
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2013-01-02
Journal Detail:
Title:  Angewandte Chemie (International ed. in English)     Volume:  52     ISSN:  1521-3773     ISO Abbreviation:  Angew. Chem. Int. Ed. Engl.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-02-04     Completed Date:  2013-08-16     Revised Date:  2014-02-05    
Medline Journal Info:
Nlm Unique ID:  0370543     Medline TA:  Angew Chem Int Ed Engl     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1718-21     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Catalytic Domain
Cyclization
Fungi / enzymology*
Metabolic Engineering
Polyketide Synthases / chemistry,  metabolism*
Transaldolase / chemistry,  metabolism
Grant Support
ID/Acronym/Agency:
ES001670/ES/NIEHS NIH HHS; R01 ES001670/ES/NIEHS NIH HHS; T32 GM080189/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
79956-01-7/Polyketide Synthases; EC 2.2.1.2/Transaldolase
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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