| Combination therapy using 9,3"-di-O-acetyl-midecamycin with beta-lactam antibiotics against Pseudomonas aeruginosa infection. | |
| | |
MedLine Citation:
|
PMID: 6798249 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The combined effect of beta-lactam antibiotics and 9,3"-di-O-acetylmidecamycin were examined in 10 patients diagnosed as having chronic respiratory tract infections and complicated urinary tract infections. Patients were initially treated with 3 to 10 g/day of beta-lactams as intravenous infusions or by oral route for a certain period, after which period they were treated concurrently with 0.3 to 0.9 g/day of 9,3"-di-O-acetylmidecamycin by oral route. Through this combination therapy eradication of P. aeruginosa was obtained in 2 cases and remarkable decrease in another 2 cases out of the 10 cases. This combination therapy was judged to be effective in these 4 cases. Of the remaining cases, P. aeruginosa was eliminated before the start of the combination therapy in 3 cases, and no change in bacterial count was noted after the combination therapy in the other 3 cases. |
| | |
Authors:
|
K Mashimo; J Y Homma; Y Iki; K Inatomi; T Kasai; O Kunii; K Shimada; H Tanimoto; T Takigami; Y Nishimura |
Related Documents
:
|
11952729 - Mycobacterium fortuitum complex endocarditis-case report and literature review. 21626069 - Primary intraocular lymphoma: a review. 8834719 - Management of mitral valve stenosis in pregnancy: case presentation and review of the l... 20032249 - Prosthetic valve endocarditis due to actinomyces neuii successfully treated with antibi... 14688049 - Antibiotic prophylaxis, body piercing and infective endocarditis. 18029099 - Endocarditis in burn patients: clinical and diagnostic considerations. 16324239 - Primary progressive multifocal leukoencephalopathy: report of a case. 21314889 - Using and writing reviews to inform your practice. 2398799 - Suicidal strangulation by ligature: three case reports. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The Japanese journal of experimental medicine Volume: 51 ISSN: 0021-5031 ISO Abbreviation: Jpn. J. Exp. Med. Publication Date: 1981 Oct |
Date Detail:
|
Created Date: 1982-03-22 Completed Date: 1982-03-22 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9800765 Medline TA: Jpn J Exp Med Country: JAPAN |
Other Details:
|
Languages: eng Pagination: 271-85 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Agammaglobulinemia / complications Aged Anti-Bacterial Agents / therapeutic use* Bronchiectasis / drug therapy Bronchitis / drug therapy Drug Therapy, Combination Female Humans Leucomycins / therapeutic use* Male Middle Aged Miocamycin Pseudomonas Infections / drug therapy*, microbiology Pseudomonas aeruginosa / immunology Pulmonary Emphysema / drug therapy Urinary Bladder, Neurogenic / drug therapy beta-Lactams / therapeutic use |
| Chemical | |
Reg. No./Substance:
|
0/Anti-Bacterial Agents; 0/Leucomycins; 0/beta-Lactams; 55881-07-7/Miocamycin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Altered resistance to Listeria monocytogenes in diabetic mice.
Next Document: Immunogenicity of purified Habu snake-venom toxoid in guinea pigs and monkeys with special reference...