Document Detail

Combination therapy for solar lentigines.
MedLine Citation:
PMID:  15552596     Owner:  NLM     Status:  MEDLINE    
Solar lentigines are benign, hyperpigmented lesions that present a significant cosmetic nuisance for many middle-aged and elderly patients with chronic accumulated sun exposure. While previous monotherapies designed to lighten these lesions offer relatively modest improvement, there are several new treatment options. Combination topical therapy using 2% mequinol/0.01% tretinoin [Solagé Topical Solution] has been shown to markedly reduce lesion darkness with few side effects. Chemical peels can give good results either alone or in combination with topical therapy. Cryotherapy is an effective and inexpensive way of treating solar lentigines while IPL and lasers are more costly treatment options. For patients desiring treatment, optimal cosmetic improvement can be achieved using a combination of topical and procedural therapies.
Patricia K Farris
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of drugs in dermatology : JDD     Volume:  3     ISSN:  1545-9616     ISO Abbreviation:  J Drugs Dermatol     Publication Date:    2004 Sep-Oct
Date Detail:
Created Date:  2004-11-19     Completed Date:  2005-04-11     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101160020     Medline TA:  J Drugs Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S23-6     Citation Subset:  IM    
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MeSH Terms
Administration, Cutaneous
Chemexfoliation / methods
Clinical Trials as Topic
Combined Modality Therapy
Cryotherapy / methods
Dermatologic Agents / administration & dosage,  therapeutic use
Laser Therapy
Lentigo / etiology,  psychology,  therapy*
Phototherapy / methods
Sunlight / adverse effects*
Treatment Outcome
Reg. No./Substance:
0/Dermatologic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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