Document Detail


Combination of telmisartan plus amlodipine in the treatment of hypertension: review of results.
MedLine Citation:
PMID:  21090924     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The rate of control of hypertension remains suboptimal despite widespread educational programs and an increasing number of novel medications. The combination of drugs with different mechanisms of action has become an alternative to improve blood pressure reduction and control, enhance adherence to the treatment and reduce adverse events. Telmisartan and amlodipine in monotherapy provide effective blood pressure lowering at all clinically relevant doses, but less than 50% of stage 1 and 2 achieve the target blood pressure. This article presents most of the relevant results of combinations of telmisartan plus amlodipine, at different doses, in hypertensive patients and a post hoc analysis of subgroups including the elderly, Type 2 diabetics, those with systolic hypertension and obese patients.
Authors:
Wille Oigman; Mario Fritsch Neves; Ronaldo Aoc Gismondi
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Expert review of cardiovascular therapy     Volume:  8     ISSN:  1744-8344     ISO Abbreviation:  Expert Rev Cardiovasc Ther     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-24     Completed Date:  2011-03-10     Revised Date:  2014-01-09    
Medline Journal Info:
Nlm Unique ID:  101182328     Medline TA:  Expert Rev Cardiovasc Ther     Country:  England    
Other Details:
Languages:  eng     Pagination:  1509-17     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Amlodipine / administration & dosage,  therapeutic use*
Angiotensin II Type 1 Receptor Blockers / administration & dosage,  therapeutic use*
Antihypertensive Agents / administration & dosage,  therapeutic use*
Benzimidazoles / administration & dosage,  therapeutic use*
Benzoates / administration & dosage,  therapeutic use*
Dose-Response Relationship, Drug
Drug Combinations
Humans
Hypertension / drug therapy*
Medication Adherence
Treatment Outcome
Chemical
Reg. No./Substance:
0/Angiotensin II Type 1 Receptor Blockers; 0/Antihypertensive Agents; 0/Benzimidazoles; 0/Benzoates; 0/Drug Combinations; 1J444QC288/Amlodipine; U5SYW473RQ/telmisartan

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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