Document Detail

Combination regimen of methylprednisolone, IV immunoglobulin, and plasmapheresis early in the treatment of acute disseminated encephalomyelitis.
MedLine Citation:
PMID:  16868969     Owner:  NLM     Status:  MEDLINE    
Acute disseminated encephalomyelitis (ADEM) is a demyelinating disease of the central nervous system that is associated with significant morbidity and mortality. Early recognition of the disease is of paramount importance; however, treatment options are limited because only case reports and small series are available in the literature. We report a case of a 42 year-old previously healthy man, whom we treated successfully with a combination regimen of methylprednisolone, IV immunoglobulin, and plasmapheresis early in the course of the disease.
Rommel P Lu; Gary Keilson
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical apheresis     Volume:  21     ISSN:  0733-2459     ISO Abbreviation:  J Clin Apher     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-12-26     Completed Date:  2007-03-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8216305     Medline TA:  J Clin Apher     Country:  United States    
Other Details:
Languages:  eng     Pagination:  260-5     Citation Subset:  IM    
Department of Medicine, Saint Vincent Hospital at Worcester Medical Center, Worcester, Massachusetts 01608, USA.
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MeSH Terms
Acyclovir / therapeutic use
Anti-Inflammatory Agents / therapeutic use*
Antiviral Agents / therapeutic use
Ceftriaxone / therapeutic use
Combined Modality Therapy
Encephalomyelitis, Acute Disseminated / drug therapy,  etiology,  therapy*
Immunoglobulins, Intravenous / therapeutic use*
Magnetic Resonance Imaging
Mannitol / therapeutic use
Methylprednisolone / therapeutic use*
Plasma Exchange*
Respiratory Tract Infections / complications
Time Factors
Vancomycin / therapeutic use
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Antiviral Agents; 0/Immunoglobulins, Intravenous; 1404-90-6/Vancomycin; 59277-89-3/Acyclovir; 69-65-8/Mannitol; 73384-59-5/Ceftriaxone; 83-43-2/Methylprednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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