Document Detail


Combination antiretroviral therapy.
MedLine Citation:
PMID:  21434758     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Combination antiretroviral therapy (cART) was one of the greatest achievements in medicine in the twentieth century. It has rapidly evolved during the last 10 years from suboptimal monotherapy to an effective triple therapy that can change the natural history of HIV-1 infection from a deadly disease to a chronic, manageable condition. However, a dreadful toll of long-term toxicity was experienced by HIV-1-infected patients in the cART era. We have recently entered in a new phase of cART, in which efficacy has been increased and toxicity minimized. Currently, the greatest challenge is to make cART available to everybody who needs it with the future prospects of HIV-1 eradication.
Authors:
Pere Domingo; Francesc Vidal
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Publication Detail:
Type:  Editorial     Date:  2011-03-24
Journal Detail:
Title:  Expert opinion on pharmacotherapy     Volume:  12     ISSN:  1744-7666     ISO Abbreviation:  Expert Opin Pharmacother     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-04-08     Completed Date:  2011-12-12     Revised Date:  2011-12-19    
Medline Journal Info:
Nlm Unique ID:  100897346     Medline TA:  Expert Opin Pharmacother     Country:  England    
Other Details:
Languages:  eng     Pagination:  995-8     Citation Subset:  IM    
Copyright Information:
© 2011 Informa UK, Ltd
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MeSH Terms
Descriptor/Qualifier:
Anti-HIV Agents / adverse effects*,  therapeutic use*
Antiretroviral Therapy, Highly Active* / adverse effects
HIV Infections / drug therapy*
HIV-1*
Humans
Treatment Outcome
Chemical
Reg. No./Substance:
0/Anti-HIV Agents
Comments/Corrections
Comment In:
Expert Opin Pharmacother. 2011 Dec;12(17):2763-4   [PMID:  21895542 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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