| Combination antiplatelet therapy: implications for pharmacists. | |
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MedLine Citation:
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PMID: 12482014 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To present two case reports of patients who received suboptimal oral antiplatelet therapy and to review recent changes in national guidelines for management of acute coronary syndromes. DATA SOURCES: Personal observation by the authors, and clinical practice guidelines and related clinical trials of the American Heart Association and the American College of Cardiology. SUMMARY: The American College of Cardiology and the American Heart Association revised the guidelines for administration of antiplatelet and anticoagulant therapy in patients with unstable angina and non-ST-segment elevation myocardial infarction in March 2002. Two cases observed by the authors illustrate the consequences of suboptimal antiplatelet therapy when a combination of two antiplatelet drugs should have been administered. CONCLUSION: Evidence from recent randomized, controlled trials led to changes in the national guidelines for administration of oral antiplatelet therapy in patients with acute coronary syndromes. Pharmacists should be aware of these changes and counsel patients about appropriate administration of antiplatelet drugs. |
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Authors:
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Robert L Talbert; Sarah A Spinier; Jean M Nappi; Michael B Bottorff |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of the American Pharmaceutical Association (Washington,D.C. : 1996) Volume: 42 ISSN: 1086-5802 ISO Abbreviation: J Am Pharm Assoc (Wash) Publication Date: 2002 Nov-Dec |
Date Detail:
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Created Date: 2002-12-16 Completed Date: 2003-01-22 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9601004 Medline TA: J Am Pharm Assoc (Wash) Country: United States |
Other Details:
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Languages: eng Pagination: 880-3 Citation Subset: IM |
Affiliation:
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College of Pharmacy, University of Texas-Austin, USA. talbert@uthscsa.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Coronary Artery Disease / drug therapy Drug Therapy, Combination Female Humans Male Middle Aged Patient Compliance Pharmaceutical Services Pharmacists Platelet Aggregation Inhibitors / administration & dosage*, adverse effects, therapeutic use* Practice Guidelines as Topic |
| Chemical | |
Reg. No./Substance:
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0/Platelet Aggregation Inhibitors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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