Document Detail

Colour duplex sonography-guided local lysis of occlusions in the femoro-popliteal region.
MedLine Citation:
PMID:  11201594     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: To evaluate colour duplex sonographic guidance of local lysis of occlusions in the femoropopliteal region. METHODS: Thirteen consecutive patients (8 female, mean age 67) with peripheral artery disease with acute and subacute occlusions in the superficial femoral or popliteal artery were included in this study. The lesions were identified by colour duplex ultrasound (Acuson 128 XP/10) After anterograde puncture the guidewire was advanced through the arterial lesions under B-mode image control. The Mewissen Infusion Catheter and a Katzen infusion wire were then accurately positioned within the lesion under B-mode image control. The fibrinolytic drugs were then inserted into the occlusions, initially 2.5 mg rt-PA as a bolus followed by Urokinase (50,000 IU/h) for 24 hours. After control duplex sonography (over 24 hours) the additional angioplasty was performed either under fluoroscopic or exclusively under ultrasound guidance. RESULTS: Eleven of 13 patients with occlusions in the femoro-popliteal region were partially recanalised after ultrasound guided local lysis and after the additional angioplasties (nine under fluoroscopic and three under ultrasound guidance) the arteries were completely recanalised. CONCLUSIONS: Our data show that not only is the positioning of the catheter and the guidewire for local lysis exclusively under colour duplex guidance possible, but also the surveillance of the local lysis and the additional angioplasty. In the case of any complications, however, easy access to angiography should be possible.
R Katzenschlager; A Ahmadi; M Atteneder; A Ugurluoglu; R Koppensteiner; E Minar; H Ehringer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International angiology : a journal of the International Union of Angiology     Volume:  19     ISSN:  0392-9590     ISO Abbreviation:  Int Angiol     Publication Date:  2000 Sep 
Date Detail:
Created Date:  2001-01-29     Completed Date:  2001-05-03     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8402693     Medline TA:  Int Angiol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  250-4     Citation Subset:  IM    
Department of Angiology, University of Vienna, Austria.
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MeSH Terms
Aged, 80 and over
Angioplasty, Balloon
Combined Modality Therapy
Femoral Artery / drug effects*,  ultrasonography
Ischemia / drug therapy*
Leg / blood supply*
Middle Aged
Popliteal Artery / drug effects*,  ultrasonography
Thrombolytic Therapy*
Ultrasonography, Doppler, Color*
Urokinase-Type Plasminogen Activator / administration & dosage*,  adverse effects
Reg. No./Substance:
EC Plasminogen Activator

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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