| Colorimetric determination of macrolide antibiotics using ferric ion. | |
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MedLine Citation:
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PMID: 18966372 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Macrolide antibiotics such as erythromycin, oleandomycin, spiromycin, and tylosin are found to react with Fe(3+) in the presence of an acetic acid-sulfuric acid mixture to form a colored product having a useful absorption band at 592 nm. Troleandomycin forms only a weakly colored product upon reaction. The molar absorptivity is about 2900 1 mol(-1) cm(-1) for erythromycin and the detection limit is 5 mug ml(-1). This colorimetric method permits the analysis of fermentation broths containing either erythromycin or tylosin without a separation step. |
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Authors:
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P A Gallagher; N D Danielson |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Talanta Volume: 42 ISSN: 0039-9140 ISO Abbreviation: Talanta Publication Date: 1995 Oct |
Date Detail:
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Created Date: 2008-10-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2984816R Medline TA: Talanta Country: England |
Other Details:
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Languages: eng Pagination: 1425-32 Citation Subset: - |
Affiliation:
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Department of Chemistry, Miami University, Oxford, OH 45056, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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