| Colorectal cancer screening differential costs for younger versus older Americans. | |
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MedLine Citation:
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PMID: 16627125 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Colorectal cancer (CRC) incidence rises with age, and most CRC arises from adenomatous polyps. It was therefore hypothesized that increased use of CRC screening and polypectomy in younger persons might yield CRC-related savings later in life for payers such as Medicare. METHODS: Using a decision analytic Markov model, the impact of increased CRC screening uptake on healthcare payers for younger Americans versus payers for older Americans, such as Medicare, was projected. RESULTS: As screening uptake increased, CRC incidence and mortality decreased, and annual costs related to CRC care and testing increased for younger persons, but decreased for older persons. Compared with current screening uptake of 40%, screening 75% of the U.S. population aged 50 to 80 increased annual costs related to CRC care and testing from 3.6 billion US dollars to 5.0 billion US dollars for 50- to 64-year-olds, but decreased annual costs from 5.9 billion US dollars to 5.6 billion US dollars for those aged 65 years and older. Sensitivity analyses suggest that future costs for other diseases could offset CRC care savings in older Americans that are attributable to screening. However, even without net cost savings for any age group, screening remained relatively cost-effective. CONCLUSIONS: Investments in screening and polypectomy in younger persons may decrease CRC-related costs, including screening and surveillance, for healthcare payers for older Americans, including Medicare. While these savings could potentially be offset by future health costs for other diseases, screening would still be cost-effective. Widespread CRC screening beginning at age 50 must remain a national priority. |
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Authors:
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Uri Ladabaum; Kathryn A Phillips |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural Date: 2006-03-23 |
Journal Detail:
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Title: American journal of preventive medicine Volume: 30 ISSN: 0749-3797 ISO Abbreviation: Am J Prev Med Publication Date: 2006 May |
Date Detail:
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Created Date: 2006-04-21 Completed Date: 2006-09-28 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8704773 Medline TA: Am J Prev Med Country: Netherlands |
Other Details:
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Languages: eng Pagination: 378-84 Citation Subset: IM |
Affiliation:
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Division of Gastroenterology, University of California-San Francisco, 94143-0538, USA. uri.ladabaum@ucsf.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Aged Aged, 80 and over Colorectal Neoplasms / diagnosis*, epidemiology, mortality Decision Support Techniques Humans Markov Chains Mass Screening / economics* Medicare / economics Middle Aged United States / epidemiology |
| Grant Support | |
ID/Acronym/Agency:
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R01 CA101849-01A1/CA/NCI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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