| Colorectal cancer presenting with dysarthria and ataxia: a case of isolated leptomeningeal metastasis. | |
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MedLine Citation:
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PMID: 22004622 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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We report the case of a 72-year-old man who presented with weight loss, anorexia and a change in bowel habit. Computed tomography (CT) of the chest, abdomen and pelvis demonstrated widespread thoracic and abdominal lymphadenopathy and a lesion within the splenic flexure. This was confirmed as an adenocarcinoma after a colonoscopic biopsy. A CT guided biopsy of the abdominal lymph node confirmed the adenocarcinoma. Within three days of admission, the patient developed worsening, progressive cerebellar symptoms that left the patient aphasic and bed bound. CT of the head was reported as normal. Magnetic resonance imaging of the head demonstrated widespread leptomeningeal metastases. We describe a case of isolated leptomeningeal metastasis from a colorectal primary tumour. |
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Authors:
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R P Lahiri; K M Burnand; A Bandi; N Farooq; T Sathesh-Kumar |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Annals of the Royal College of Surgeons of England Volume: 93 ISSN: 1478-7083 ISO Abbreviation: Ann R Coll Surg Engl Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7506860 Medline TA: Ann R Coll Surg Engl Country: England |
Other Details:
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Languages: eng Pagination: 133-5 Citation Subset: IM |
Affiliation:
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Department of General Surgery, Norfolk and Norwich University Hospital, Norwich, UK; 11 Pigg Lane, Norwich, Norfolk NR3 1RS, UK. rajlahiri@doctors.org.uk. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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