| Colorectal cancer and ischaemic heart disease: an uncommon inheritance! | |
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MedLine Citation:
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PMID: 1463976 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study reports the relative risk of death from cancer and from coronary artery disease in 1,811 first-degree relatives of 205 young colorectal cancer probands. The elevation in the risks of death from cancer (eg colon 3.6; rectum 2.0; uterus 1.8; cervix 2.3) is consistent with, though of lower magnitude than previous studies. An unexpected find was a highly significant deficit in coronary deaths. Recently discovered molecular associations between colon cancer and cholesterol metabolism suggest that further family studies of bowel cancer and heart disease in a variety of populations may be worthwhile. |
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Authors:
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F Kee; B J Collins |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) Volume: 1 ISSN: 0959-8278 ISO Abbreviation: Eur. J. Cancer Prev. Publication Date: 1992 Feb |
Date Detail:
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Created Date: 1993-01-15 Completed Date: 1993-01-15 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9300837 Medline TA: Eur J Cancer Prev Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 149-52 Citation Subset: IM |
Affiliation:
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Department of Epidemiology and Public Health, Queen's University of Belfast, Northern Ireland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cause of Death Colonic Neoplasms / complications*, genetics*, mortality Female Humans Middle Aged Myocardial Ischemia / complications*, genetics*, mortality Northern Ireland / epidemiology Pancreatic Neoplasms / complications, mortality Rectal Neoplasms / complications*, genetics*, mortality Risk Factors Uterine Cervical Neoplasms / complications, mortality Uterine Neoplasms / complications, mortality |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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