Document Detail


Color velocity imaging quantification in the detection of intracranial collateral flow.
MedLine Citation:
PMID:  12105355     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND PURPOSE: The development of intracranial collateral circulation is associated with a lower risk of stroke. A noninvasive technique that can reliably detect the presence of intracranial collaterals would be a valuable factor in the assessment of risk in patients with occlusive cerebrovascular disease. METHODS: Color velocity imaging quantification was used to measure the blood flow volume of the common carotid and vertebral arteries in 40 patients with carotid occlusive disease. The blood flow volumes in these arteries were correlated with angiographic evidence of collaterals to establish the best cutoffs for detecting intracranial collateral circulation. RESULTS: A blood flow volume of either > or =370 mL/min in the common carotid artery or > or =120 mL/min in the vertebral artery was indicative of the presence of intracranial collaterals. The sensitivity and specificity for the common carotid artery were 92.3% [95% confidence interval (CI), 62.1 to 99.6] and 92.1% (95% CI, 77.5 to 97.9), respectively. The sensitivity and specificity for the vertebral artery were 75.0% (95% CI, 35.6 to 95.5) and 87.5% (95% CI, 66.5 to 96.7), respectively. CONCLUSIONS: Color velocity imaging quantification offers a noninvasive, accurate method for detecting the presence of intracranial collateral circulation and quantifying its magnitude. This technique would be a useful adjunct in screening or continuous monitoring of patients with severe carotid occlusive disease.
Authors:
S S Y Ho; C Metreweli; C H Yu
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Stroke; a journal of cerebral circulation     Volume:  33     ISSN:  1524-4628     ISO Abbreviation:  Stroke     Publication Date:  2002 Jul 
Date Detail:
Created Date:  2002-07-09     Completed Date:  2002-08-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0235266     Medline TA:  Stroke     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1795-8     Citation Subset:  IM    
Affiliation:
Department of Radiology and Organ Imaging, Prince of Wales Hospital, Yuen Chau Kok, Shatin, Hong Kong. stellaho@cuhk.edu.hk
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MeSH Terms
Descriptor/Qualifier:
Aged
Angiography, Digital Subtraction
Blood Flow Velocity / physiology
Carotid Artery, Common / radiography,  ultrasonography
Carotid Stenosis / radiography,  ultrasonography*
Cerebral Angiography
Cerebrovascular Circulation / physiology*
Collateral Circulation / physiology*
Female
Humans
Male
Predictive Value of Tests
Sensitivity and Specificity
Severity of Illness Index
Ultrasonography, Doppler, Color*
Vertebral Artery / radiography,  ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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