| Color and pulsed Doppler sonography, gray-scale imaging, and serum CA 125 in the assessment of adnexal disease. | |
| | |
MedLine Citation:
|
PMID: 8692517 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To compare color and pulsed Doppler sonography with gray-scale ultrasound imaging and serum CA 125 levels in establishing accurate preoperative diagnoses of adnexal masses. METHODS: Medical records of 109 patients referred with preexisting adnexal lesions were reviewed retrospectively by comparing preoperative ultrasonic data (gray-scale imaging and color and pulsed Doppler findings) with serum CA 125 levels. RESULTS: Eighty-three masses were removed surgically, confirming seven malignancies and 76 benign tumors, and 26 masses were followed; 15 regressed and 11 persisted. Color and pulsed Doppler sonography showed the highest sensitivity, followed by gray-scale imaging, whereas serum CA 125 levels revealed the highest specificity in distinguishing malignant from benign adnexal tumors. All three methods had high negative predictive values (96-100%), whereas only serum CA 125 had a positive predictive value greater than 50%. CONCLUSION: Color and pulsed Doppler sonography, which demonstrate a tumor angiogenic activity, are as accurate as gray-scale imaging in the assessment of adnexal lesions. Together with serum CA 125 marker levels, they produce high negative predictive values, providing reassurance that an adnexal mass is benign. |
| | |
Authors:
|
M Predanic; N Vlahos; J A Pennisi; M Moukhtar; F A Aleem |
Related Documents
:
|
21622637 - Pigmented villonodular synovitis of the ankle: radiologic characteristics. 8037037 - Detection of soft-tissue hyperemia: value of power doppler sonography. 12011547 - Contrast transcranial doppler ultrasound in the detection of right-to-left shunts: comp... 2681827 - A comparison of transvaginal and abdominal ultrasound in visualizing the first trimeste... 12296437 - Hyperattenuating aortic wall on postmortem computed tomography (pmct). 17885187 - Computer-aided detection of colorectal polyps: can it improve sensitivity of less-exper... |
Publication Detail:
|
Type: Clinical Trial; Comparative Study; Journal Article |
Journal Detail:
|
Title: Obstetrics and gynecology Volume: 88 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 1996 Aug |
Date Detail:
|
Created Date: 1996-08-26 Completed Date: 1996-08-26 Revised Date: 2009-10-26 |
Medline Journal Info:
|
Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 283-8 Citation Subset: AIM; IM |
Affiliation:
|
Department of Obstetrics and Gynecology, Brookdale University Hospital and Medical Center, Brooklyn, New York, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adnexal Diseases
/
blood*,
ultrasonography* Adult Aged CA-125 Antigen / blood* Female Humans Middle Aged Predictive Value of Tests Preoperative Care ROC Curve Reproducibility of Results Sensitivity and Specificity Ultrasonography, Doppler, Color* Ultrasonography, Doppler, Pulsed* |
| Chemical | |
Reg. No./Substance:
|
0/CA-125 Antigen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Pelvic lymph node metastasis in endometrial cancer with no myometrial invasion.
Next Document: Infertility treatment dropout and insurance coverage.