Document Detail


Color and power Doppler US for diagnosing carpal tunnel syndrome and determining its severity: a quantitative image processing method.
MedLine Citation:
PMID:  21900619     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To determine whether intraneural vascularity seen at color Doppler ultrasonography (US) can be used to diagnose carpal tunnel syndrome (CTS) and to evaluate an image processing method for quantifying the severity of CTS on the basis of this vascularity.
MATERIALS AND METHODS: This study was approved by the university ethics review committee. One hundred one patients with clinical evidence of CTS and 55 healthy control subjects were enrolled. Electrodiagnostic testing (EDT) was performed in all participants, and the presence of intraneural vascularity was evaluated with color Doppler US. An image processing program was designed by using software to determine the sum of pixels in the intraneural vascular area on power Doppler US scans of the median nerve. The relationship between the number of pixels and the severity of the abnormality at EDT was determined.
RESULTS: The sensitivity (83%) and specificity (89%) of intraneural vascularity in the diagnosis of CTS were similar to those of EDT (81% and 84%, respectively). Intraneural vascularity was seen in 91.4% of patients with mild CTS and 100% of patients with moderate or severe CTS. In participants with positive intraneural vascularity, the sum of pixels in the intraneural vascular area was significantly higher in patients than in control subjects and paralleled the severity of the abnormality at EDT (P < .01).
CONCLUSION: Color Doppler US can be used to accurately diagnose CTS. By processing the recorded power Doppler images and determining the number of pixels in the intraneural vascular area, the severity of CTS can be assessed. 2011 Supplemental material: http://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.11110150/-/DC1.
Authors:
Ahmad Reza Ghasemi-Esfe; Omid Khalilzadeh; Seyed Mehran Vaziri-Bozorg; Mahdie Jajroudi; Madjid Shakiba; Mehdi Mazloumi; Maryam Rahmani
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Publication Detail:
Type:  Journal Article     Date:  2011-09-07
Journal Detail:
Title:  Radiology     Volume:  261     ISSN:  1527-1315     ISO Abbreviation:  Radiology     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-10-20     Completed Date:  2011-12-07     Revised Date:  2012-03-29    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  499-506     Citation Subset:  AIM; IM    
Copyright Information:
RSNA, 2011
Affiliation:
Advanced Diagnostic and Interventional Radiology Research Center, Imam Hospital, Tehran University of Medical Sciences, Keshavarz Blvd, Tehran 13145-784, Iran.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Carpal Tunnel Syndrome / ultrasonography*
Case-Control Studies
Cross-Sectional Studies
Electrodiagnosis
Female
Humans
Image Interpretation, Computer-Assisted*
Male
Median Nerve / blood supply*,  ultrasonography*
Middle Aged
Sensitivity and Specificity
Severity of Illness Index
Ultrasonography, Doppler / methods*
Ultrasonography, Doppler, Color
Comments/Corrections
Comment In:
Radiology. 2012 Mar;262(3):1043-4   [PMID:  22357906 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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