| Color Doppler sonography of the prostate. | |
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MedLine Citation:
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PMID: 8912444 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Digital rectal examination, prostate-specific antigen and transrectal sonography (TRS) are the main diagnostic tools for evaluating men at risk for carcinoma of the prostate (PCa). PCa has a hypoechoic echo pattern via TRS in 60- 85% of cases. Hypoechoic areas are observed, however, in benign prostatic hyperplasia (BPH) as well. For this reason, TRS yields a low specificity and sensitivity in detecting PCa in screening programs. Additional data, independent of the grey scale information available via TRS, can be obtained by using the innovative technology of color Doppler sonography. This imaging modality allows simultaneous real-time sonographic visualization and evaluation of vascular structures. The present study analyzes to what extent the analysis of blood flow perfusion of prostatic parenchyma can provide further information concerning the pathologic alterations occurring in abnormal prostate tissue. Blood flow phenomena were reproducibly demonstrated in the prostate and in the periprostatic tissue with the color-coded Doppler sonography (CD-TRS). 31 patients with the diagnosis of BPH could be separated into two different groups according to the findings with TRS and CD-TRS. In contrast, patients with histologically proven PCa (n = 16) had subjectively increased perfusion rates. Blood flow phenomena were analyzed using computer-calculated resistive index and pulsatility index as evaluations of flow and frequency. A preliminary analysis of the wave-form characteristics shows that flow in the prostate gland is associated with a high resistive index in both PCa and BPH. The mean frequency demonstrated in the pulsatility index appears to be high in PCa, but low in BPH cases. Further studies are needed to verify the described factors' abilities to differentiate prostate tissue as either PCa or BPH. |
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Authors:
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S M Miller; R Ackermann |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article |
Journal Detail:
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Title: Urologia internationalis Volume: 57 ISSN: 0042-1138 ISO Abbreviation: Urol. Int. Publication Date: 1996 |
Date Detail:
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Created Date: 1997-02-12 Completed Date: 1997-02-12 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0417373 Medline TA: Urol Int Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 158-64 Citation Subset: IM |
Affiliation:
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Department of Urology, University of Düsseldorf, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Humans Male Prostate / blood supply, pathology, ultrasonography* Prostatic Hyperplasia / ultrasonography Prostatic Neoplasms / blood supply, pathology, ultrasonography Regional Blood Flow Sensitivity and Specificity Ultrasonography, Doppler, Color / methods* Urethra / blood supply, ultrasonography |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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