Document Detail


Color Doppler imaging of fibroadenomas of the breast with histopathologic correlation.
MedLine Citation:
PMID:  15293297     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: This study was conducted to characterize the spatial distribution of blood vessels in breast fibroadenomas. METHODS: We performed a prospective study to map the anatomic distribution of the vessels in 29 fibroadenomas of the breast using color Doppler sonography. We categorized the detected vessels according to their location in or on the fibroadenoma, counted the different types of vessels, and tested for correlations between vessel distributions or numbers and histopathologic findings. RESULTS: Blood flow was demonstrated in 24/29 (83%) of fibroadenomas. We found 3 vessel types: feeding vessels, which are prominent vessels leading from the surrounding breast tissue into the fibroadenoma; capsular vessels, which are located within the tissue capsule; and segmental vessels, which are located within the fibrous septa of the fibroadenoma. Capsular and segmental vessels were demonstrated in 23/24 (96%) and 24/24 (100%) of the cases, respectively. Feeding vessels were seen in 12/24 (50%) of the cases. Histopathologic analysis revealed the same location and distribution of the vessels as color Doppler imaging. However, there was no correlation between numbers of vessels counted on sonograms and on histopathologic specimens. CONCLUSIONS: Examination of the vascularity demonstrated on color Doppler imaging helps in the diagnosis of benign breast neoplasms such as fibroadenomas.
Authors:
Selwyn Strano; Eva C Gombos; Orith Friedland; Marta Mozes
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical ultrasound : JCU     Volume:  32     ISSN:  0091-2751     ISO Abbreviation:  J Clin Ultrasound     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-08-04     Completed Date:  2004-12-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401663     Medline TA:  J Clin Ultrasound     Country:  United States    
Other Details:
Languages:  eng     Pagination:  317-22     Citation Subset:  IM    
Copyright Information:
Copyright 2004 Wiley Periodicals, Inc.
Affiliation:
Rachel Nash Comprehensive Breast Center, Bet Ofer, 5 Nachum Heftzadi St., Jerusalem, 95484, Israel.
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MeSH Terms
Descriptor/Qualifier:
Adult
Breast Neoplasms / blood supply,  pathology,  ultrasonography*
Diagnosis, Differential
Female
Fibroadenoma / blood supply,  pathology,  ultrasonography*
Humans
Middle Aged
Neovascularization, Pathologic / ultrasonography*
Prospective Studies
Ultrasonography, Doppler, Color*

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