| Color Doppler flow mapping of the patent ductus arteriosus in very low birthweight neonates: echocardiographic and clinical findings. | |
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MedLine Citation:
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PMID: 7997425 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Forty-eight preterm infants (mean birthweight 1.0 +/- 0.3 kg; mean gestational age 28 +/- 3 weeks) underwent serial echocardiograms and physical examinations in order to determine the correlation between color Doppler flow mapping (CDFM) results and physical findings of a patent ductus arteriosus (PDA), the predictive value of early CDFM as an indicator of subsequent requirement for treatment of a PDA, and to determine the direction and duration of ductal shunting and the rate of ductal closure and opening. CDFM analysis and cardiac physical examination of left-to-right ductal shunting were usually concordant in infants with a large PDA shunt, the most reliable physical finding being increased precordial activity. CDFM studies on day 2 or 3 of postnatal life had prognostic value with regard to subsequent need for closing the PDA. Additional findings included the absence of right-to-left PDA shunting in infants < 1 kg and < 28 weeks gestation and the absence of ductal reopening in infants in whom it had closed spontaneously. After complete PDA closure using indomethacin, subsequent ductal reopening is uncommon, except in infants < 25 weeks gestation and < 700 g bodyweight. |
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Authors:
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D A Roberson; N H Silverman |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pediatric cardiology Volume: 15 ISSN: 0172-0643 ISO Abbreviation: Pediatr Cardiol Publication Date: 1994 Sep-Oct |
Date Detail:
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Created Date: 1995-01-13 Completed Date: 1995-01-13 Revised Date: 2008-02-20 |
Medline Journal Info:
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Nlm Unique ID: 8003849 Medline TA: Pediatr Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 219-24 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, University of California, San Francisco. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Ductus Arteriosus, Patent
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diagnosis,
therapy,
ultrasonography* Echocardiography, Doppler, Color* Humans Indomethacin / therapeutic use Infant, Low Birth Weight / physiology* Infant, Newborn Infant, Premature Physical Examination Prognosis Prospective Studies |
| Chemical | |
Reg. No./Substance:
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53-86-1/Indomethacin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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