Document Detail


Colonoscopy after CT diagnosis of diverticulitis to exclude colon cancer: a systematic literature review.
MedLine Citation:
PMID:  22517956     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To estimate the prevalence of underlying adenocarcinoma of the colon in patients in whom acute diverticulitis was diagnosed at computed tomography (CT) and to compare that to the prevalence of colon cancer in the general population.
MATERIALS AND METHODS: A comprehensive literature review was performed to find articles in which patients with CT diagnosis of acute diverticulitis underwent surgery, colonoscopy, or barium enema study within 24 weeks. Patients meeting these criteria were included for analysis. A pooled prevalence of cancer was calculated on the basis of a random effects model and compared qualitatively with the prevalence of cancer in the general population. The 95% confidence intervals around the prevalence of cancer in the study populations were determined.
RESULTS: Ten articles met the inclusion criteria. Data from these articles included only 771 patients who underwent surgery, colonoscopy, or barium enema study within 24 weeks of diagnosis. Fourteen patients were found to have colon cancer, for a prevalence of 2.1% (95% confidence interval: 1.2%, 3.2%). This compares to a calculated estimated prevalence of 0.68% among U.S. adults older than 55 years.
CONCLUSION: There are limited data to support the recommendation to perform colonoscopy after a diagnosis of acute diverticulitis.
Authors:
Victor F Sai; Fernando Velayos; John Neuhaus; Antonio C Westphalen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Radiology     Volume:  263     ISSN:  1527-1315     ISO Abbreviation:  Radiology     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-04-20     Completed Date:  2012-07-19     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  383-90     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA. victor.sai@ucsf.edu
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / diagnosis*,  epidemiology,  radiography
Barium Sulfate / diagnostic use
Colonic Neoplasms / diagnosis*,  epidemiology,  radiography
Colonoscopy*
Confidence Intervals
Contrast Media / diagnostic use
Diagnosis, Differential
Diverticulitis, Colonic / diagnosis*,  epidemiology,  radiography
Humans
Predictive Value of Tests
Prevalence
Tomography, X-Ray Computed*
Chemical
Reg. No./Substance:
0/Contrast Media; 7727-43-7/Barium Sulfate
Comments/Corrections
Erratum In:
Radiology. 2012 Jul;264(1):306

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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