Document Detail

Colonic transit investigated by radiopaque markers in females with irritable bowel syndrome: no correlation with symptoms and chronic stress.
MedLine Citation:
PMID:  9167223     Owner:  NLM     Status:  MEDLINE    
The aim of this study was to investigate the correlation between colonic transit and chronic stress in the irritable bowel syndrome (IBS). Total and segmental colonic transit was studied with radiopaque markers in 16 females with irritable bowel syndrome and in 20 matched controls. The transit times were correlated with symptoms and with scores of some psychological tests reflecting stress or susceptibility to stress: the life events scale of Holmes and Rahe, the Jenkins activity survey for type-A behaviour, the MMPI hostility scale and the Dukes questionnaire for social support. In females with irritable bowel syndrome, prolonged transit was observed on the right colon in 43% of cases, on the left colon in 25% of cases, on the rectosigmoid in no case, on the total colon in 31% of cases. No subject had accelerated colonic transit. In irritable bowel syndrome, life events scores were high in 63% of cases, 69% had type-A behaviour, 50% had high scores for hostility and 69% had impaired social support. All these parameters were impaired as compared to controls. No correlation was detected between stress factors and colonic transit.
D L Dumitraşcu; S Grănescu
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Romanian journal of internal medicine = Revue roumaine de médecine interne     Volume:  34     ISSN:  1220-4749     ISO Abbreviation:  Rom J Intern Med     Publication Date:    1996 Jul-Dec
Date Detail:
Created Date:  1997-07-17     Completed Date:  1997-07-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9304507     Medline TA:  Rom J Intern Med     Country:  ROMANIA    
Other Details:
Languages:  eng     Pagination:  225-31     Citation Subset:  IM    
Third Medical Department, University of Medicine and Pharmacy, Cluj-Napoca, Romania.
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MeSH Terms
Chronic Disease
Colon / physiopathology*,  radiography
Colonic Diseases, Functional / physiopathology*,  psychology,  radiography
Contrast Media*
Gastrointestinal Transit*
Life Change Events
Middle Aged
Stress, Psychological / physiopathology*,  psychology,  radiography
Time Factors
Type A Personality
Reg. No./Substance:
0/Contrast Media

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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