Document Detail

Colonic pressure data processing based on independent component analysis.
MedLine Citation:
PMID:  20836747     Owner:  NLM     Status:  MEDLINE    
The Colonic manometry is an important technique to evaluate human colonic motor functions, which are critical for doctors to understand the pathology of intestinal diseases like slow transit constipation (STC) and colonic inertia (CI). However, in the obtained pressure signals, several patterns of colonic motor activities as well as noises mixed together, which made it difficult to observe the information people really needed. In this article, a new method was proposed to extract patterns of colonic motility from the mixed signals, so that researchers could study them thoroughly. Colonic pressure recordings from 26 volunteers were obtained by the water-perfused manometry catheters. Then independent component analysis (ICA) was introduced, which successfully separated colonic motility patterns and noises into four independent components. And according to the rhythm of contractions examined by ICA, subjects' colonic motility could be divided into three types: regular rhythm (12 subjects), slow rhythm (8 subjects) and disordered (6 subjects), which exactly accorded with their original diagnosis.
C Pan; S P Tian; G Z Yan; K D Wang
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-09-14
Journal Detail:
Title:  Journal of medical engineering & technology     Volume:  34     ISSN:  1464-522X     ISO Abbreviation:  J Med Eng Technol     Publication Date:    2010 Oct-Nov
Date Detail:
Created Date:  2010-10-18     Completed Date:  2011-02-03     Revised Date:  2012-06-11    
Medline Journal Info:
Nlm Unique ID:  7702125     Medline TA:  J Med Eng Technol     Country:  England    
Other Details:
Languages:  eng     Pagination:  415-21     Citation Subset:  IM    
Department of Information Measurement Technology and Instruments, Shanghai Jiao Tong University, Shanghai 200240, China.
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MeSH Terms
Colon* / physiology,  physiopathology
Constipation / physiopathology
Gastrointestinal Motility / physiology*
Manometry / methods*
Principal Component Analysis
Signal Processing, Computer-Assisted*

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