| Colonic perforation induced by short term use of slow release diclofenac. | |
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MedLine Citation:
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PMID: 22538042 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Upper gastrointestinal (GI) toxicity of non-steroidal anti-inflammatory drugs (NSAIDs) is well characterized. There is also documented data regarding their adverse effects on lower GI tract, like colonic strictures, inflammatory bowel disease and complications of diverticular disease in the form of abscess or perforation. But there are only two case reports published previously that show colonic perforation due to use of NSAIDs solely. We present here a case of colonic perforation induced by short-term use of slow release diclofenac in a young man. Colonic perforation should be considered as the possible diagnosis in patients with acute abdomen and NSAIDs to be one of the differentials if other possibilities are ruled out. |
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Authors:
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Noman Shahzad; Asif Maqbool; Tooba Mahmud Gauhar; Khwaja Muhammad Azim |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP Volume: 22 ISSN: 1681-7168 ISO Abbreviation: J Coll Physicians Surg Pak Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-04-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9606447 Medline TA: J Coll Physicians Surg Pak Country: Pakistan |
Other Details:
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Languages: eng Pagination: 328-9 Citation Subset: IM |
Affiliation:
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East Surgical Ward, Mayo Hospital, Lahore. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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