Document Detail

Colonic mucosal tears in collagenous colitis.
MedLine Citation:
PMID:  16716973     Owner:  NLM     Status:  MEDLINE    
In general, the colonic mucosa is macroscopically normal in collagenous colitis, although minor, non-specific abnormalities may be found. Significant endoscopic abnormalities, "mucosal tears" representing longitudinal mucosal lacerations, have been reported in a few patients with collagenous colitis. We report the cases of three women with collagenous colitis and mucosal tears detected at the index colonoscopy in order to illustrate the endoscopic characteristics and review the literature. Including the present cases, a total of 12 patients with mucosal tears and collagenous colitis have been reported. In 10 patients, the mucosal lacerations involved the ascending or the transverse colon. Three of the 12 patients had a colonic perforation immediately after the colonoscopy. The colonoscopist should be aware that the risk of perforation is likely to be increased when mucosal tears are present.
Anna Wickbom; Magnus Lindqvist; Johan Bohr; Kjell-Arne Ung; Jan Bergman; Sune Eriksson; Curt Tysk
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian journal of gastroenterology     Volume:  41     ISSN:  0036-5521     ISO Abbreviation:  Scand. J. Gastroenterol.     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-05-23     Completed Date:  2006-11-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0060105     Medline TA:  Scand J Gastroenterol     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  726-9     Citation Subset:  IM    
Division of Gastroenterology, Department of Medicine, Orebro University Hospital, Orebro, Sweden.
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MeSH Terms
Anti-Inflammatory Agents / therapeutic use
Budesonide / therapeutic use
Chronic Disease
Colitis, Collagenous / complications*,  drug therapy,  pathology
Colon / injuries*
Colonoscopy / adverse effects
Follow-Up Studies
Intestinal Mucosa / pathology*
Intestinal Perforation / etiology*,  pathology
Time Factors
Treatment Outcome
Reg. No./Substance:
0/Anti-Inflammatory Agents; 51333-22-3/Budesonide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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