Document Detail


Colonic lymphoid hyperplasia in melanosis coli.
MedLine Citation:
PMID:  11473472     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe the case of a patient with Rett syndrome, a syndrome characterized by progressive infant encephalopathy, developmental delay, dementia, autism, ataxia, microcephaly, spastic paraparesis, and autonomic neuropathy with constipation. At colonoscopy, multiple foci of tiny white, sessile, polypoid lesions were seen throughout the colon and rectum, mimicking the appearances of small hyperplastic or adenomatous polyps, associated with generalized melanosis coli. This is the first case to our knowledge describing melanosis coli in a patient with Rett syndrome. As melanosis pigment deposition is characteristically not seen in lymphoid tissue, the lymphoid tissue was identifiable at endoscopy as multiple white nodules mimicking generalized colonic polyposis throughout the colon. We discuss the likely mechanisms of lymphoid hyperplasia and coexistent melanosis coli in Rett syndrome.
Authors:
C B Pearce; H Martin; H D Duncan; P M Goggin; D N Poller
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of pathology & laboratory medicine     Volume:  125     ISSN:  0003-9985     ISO Abbreviation:  Arch. Pathol. Lab. Med.     Publication Date:  2001 Aug 
Date Detail:
Created Date:  2001-07-27     Completed Date:  2001-08-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7607091     Medline TA:  Arch Pathol Lab Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1110-2     Citation Subset:  AIM; IM    
Affiliation:
Queen Alexandra Hospital, Portsmouth PO6 3LY, United Kingdom.
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MeSH Terms
Descriptor/Qualifier:
Abdominal Pain
Adult
Colon / pathology*
Colonic Diseases / complications,  diagnosis*,  pathology
Colonoscopy
Diagnosis, Differential
Female
Humans
Hyperplasia
Intestinal Mucosa / pathology
Lymphoid Tissue / pathology
Melanosis / complications,  diagnosis*,  pathology
Rett Syndrome / complications*,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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