Document Detail

Collective variable modelling of nucleic acids.
MedLine Citation:
PMID:  10322207     Owner:  NLM     Status:  MEDLINE    
Collective variable models continue to contribute to our knowledge of nucleic acids. The past year has seen considerable progress both in modelling sequence-dependent effects on nucleic acid conformation and in understanding how proteins or external stresses influence nucleic acid structure. Algorithmic developments have also allowed collective models to be applied to studies of thermal fluctuations and dynamics. For larger systems, models with varying degrees of resolution are being refined and applied to nucleic acids containing hundreds or thousands of nucleotides.
I Lafontaine; R Lavery
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in structural biology     Volume:  9     ISSN:  0959-440X     ISO Abbreviation:  Curr. Opin. Struct. Biol.     Publication Date:  1999 Apr 
Date Detail:
Created Date:  1999-08-20     Completed Date:  1999-08-20     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9107784     Medline TA:  Curr Opin Struct Biol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  170-6     Citation Subset:  IM    
Laboratoire de Biochimie Théorique, CNRS UPR 9080, Institut de Biologie Physico-Chimique, 13 rue Pierre et Marie Curie, Paris, 75005, France.
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MeSH Terms
DNA / chemistry
Models, Molecular
Nucleic Acid Conformation
Nucleic Acids / chemistry*
Reg. No./Substance:
0/Nucleic Acids; 9007-49-2/DNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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