| Collateral arterial formation. Lymph draining ischemic kidneys contains a neovascular stimulating agent of high molecular weight. | |
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MedLine Citation:
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PMID: 2579930 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An agent has been identified in lymph from rat kidneys rendered ischemic by partial renal artery occlusion that induces a striking neovascular response in a hamster cheek-pouch assay system. The factor has a high molecular weight, cannot be identified in lymph from normal kidneys, and is associated with a marked increase in vascularity and in endothelial cell turnover in the cheek pouch employed for assay. This factor may play an important role in the production of the collateral arterial circulation found in the presence of renal artery stenosis and renal ischemia. |
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Authors:
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N K Hollenberg; A J Paskins-Hurlburt; H L Abrams |
Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Investigative radiology Volume: 20 ISSN: 0020-9996 ISO Abbreviation: Invest Radiol Publication Date: 1985 Jan-Feb |
Date Detail:
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Created Date: 1985-05-09 Completed Date: 1985-05-09 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0045377 Medline TA: Invest Radiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 58-61 Citation Subset: IM; S |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angiogenesis Inducing Agents
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analysis* Animals Autoradiography Cricetinae Female Growth Substances / analysis* Ischemia* Kidney / blood supply* Lymph / analysis* Male Neovascularization, Pathologic* Rats Renal Artery Obstruction / complications Thymidine / diagnostic use |
| Grant Support | |
ID/Acronym/Agency:
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GM 18674/GM/NIGMS NIH HHS; HL 05832/HL/NHLBI NIH HHS; HL 11668/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Angiogenesis Inducing Agents; 0/Growth Substances; 50-89-5/Thymidine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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