Document Detail

Collagen remodeling during decidualization in the mouse.
MedLine Citation:
PMID:  3719669     Owner:  NLM     Status:  MEDLINE    
An ultrastructural study of the features and distribution of collagen fibrils was performed in the endometrium of virgin and pregnant (2nd to 11th day) mice. Collagen-containing structures were observed in the cytoplasm of fibroblasts on the 2nd day of pregnancy. Treatment of tissues with lanthanum nitrate established that these structures were intracytoplasmic. Their association with lysosome-like bodies suggested the occurrence of intracellular digestion of collagen, probably connected with remodeling of the endometrial stroma prior to decidualization. On the 4th day of pregnancy, very few collagen fibrils were present in the intercellular space. From the 6th day of pregnancy onwards, "thick" collagen fibrils were observed between decidual cells. The diameter of these fibrils measured up to 300 nm whereas the fibrils present in the endometrium of virgin mice measured 40-68 nm.
T M Zorn; E M Bevilacqua; P A Abrahamsohn
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cell and tissue research     Volume:  244     ISSN:  0302-766X     ISO Abbreviation:  Cell Tissue Res.     Publication Date:  1986  
Date Detail:
Created Date:  1986-07-25     Completed Date:  1986-07-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0417625     Medline TA:  Cell Tissue Res     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  443-8     Citation Subset:  IM    
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MeSH Terms
Collagen / metabolism*
Decidua / metabolism,  ultrastructure*
Gestational Age
Microscopy, Electron
Reg. No./Substance:

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