| Collagen in the esophageal mucosa of patients with progressive systemic sclerosis (PSS). | |
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MedLine Citation:
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PMID: 6084918 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Eighteen consecutive patients with an established diagnosis of Progressive Systemic Sclerosis (PSS) underwent different investigative procedures to determine possible esophageal involvement. Esophageal sclerosis was demonstrated by X-ray and manometry in 13 patients. In all patients endoscopic biopsies of esophageal mucosa were obtained. In all biopsies the concentrations of hydroxyproline, hydroxylysine and proline were determined. Patients suffering from PSS involving the esophagus were found to have a significantly higher concentration of collagen specific amino acids (hydroxyproline and hydroxylysine) in the esophageal mucosa (endoscopic obtainable biopsies) than patients with PSS not affecting the esophagus. |
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Authors:
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L Hendel; T Ammitzbøll; K Dirksen; M Petri |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta dermato-venereologica Volume: 64 ISSN: 0001-5555 ISO Abbreviation: Acta Derm. Venereol. Publication Date: 1984 |
Date Detail:
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Created Date: 1985-04-10 Completed Date: 1985-04-10 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370310 Medline TA: Acta Derm Venereol Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 480-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Biopsy Collagen / physiology* Esophagus / analysis*, pathology Female Humans Male Middle Aged Mucous Membrane / analysis Scleroderma, Systemic / complications, pathology* |
| Chemical | |
Reg. No./Substance:
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9007-34-5/Collagen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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