Document Detail


Collagen dysplasia in a litter of Garafiano shepherd dogs.
MedLine Citation:
PMID:  8940898     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A connective tissue disease resembling the human Ehlers-Danlos syndrome is reported in three Garafiano shepherd dogs from the same litter. The clinical signs included skin hyperextensibility and fragility, joint laxity, and ocular lesions. Microscopical studies showed abnormalities in the packing of collagen in fibrils and fibres in the skin. Systemic connective tissue defects were demonstrated in one necropsied puppy.
Authors:
F Rodriguez; P Herráez; A Espinosa de los Monteros; P Calabuig; J L Rodríguez
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Zentralblatt für Veterinärmedizin. Reihe A     Volume:  43     ISSN:  0514-7158     ISO Abbreviation:  Zentralbl Veterinarmed A     Publication Date:  1996 Oct 
Date Detail:
Created Date:  1997-01-23     Completed Date:  1997-01-23     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0331323     Medline TA:  Zentralbl Veterinarmed A     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  509-12     Citation Subset:  IM    
Affiliation:
Department of Histology and Pathological Anatomy, Veterinary Faculty, University of Las Palmas de Gran Canaria, Spain.
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MeSH Terms
Descriptor/Qualifier:
Animals
Animals, Newborn / metabolism,  physiology*
Collagen / analysis,  metabolism,  ultrastructure
Collagen Diseases / complications,  diagnosis,  veterinary*
Connective Tissue Diseases / diagnosis,  physiopathology,  veterinary
Dog Diseases / diagnosis*,  pathology,  physiopathology*
Dogs
Eye Diseases / etiology,  physiopathology,  veterinary
Female
Joint Instability / etiology,  physiopathology,  veterinary
Lameness, Animal / etiology,  physiopathology
Male
Microscopy, Electron / veterinary
Skin / chemistry,  metabolism,  pathology
Chemical
Reg. No./Substance:
9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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