Document Detail

Collagen composition and ultrastructure of the so-called amianthoid fibres in palisaded myofibroblastoma. Ultrastructural and immunohistochemical study.
MedLine Citation:
PMID:  1381437     Owner:  NLM     Status:  MEDLINE    
A very prominent feature of the recently described intranodal palisaded myofibroblastoma is the occurrence of stellate crystalline extracellular deposits known as 'amianthoid fibres', and thought to represent abnormally thick collagen fibrils. We showed at the ultrastructural level that these deposits are composed of fibrils with the periodicity and width typical of normal native collagen. Using antibodies directed against various extracellular components, we have determined that these structures contain type I and III collagens. Our results indicate that the crystalloid deposits in intranodal palisaded myofibroblastoma called 'amianthoid fibres' do not contain giant collagen fibrils widely regarded as characteristic of the morphological concept 'amianthoid' in other locations.
A Skálová; M Michal; A Chlumská; I Leivo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of pathology     Volume:  167     ISSN:  0022-3417     ISO Abbreviation:  J. Pathol.     Publication Date:  1992 Jul 
Date Detail:
Created Date:  1992-10-08     Completed Date:  1992-10-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0204634     Medline TA:  J Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  335-40     Citation Subset:  IM    
Department of Pathology, Charles University, Medical Faculty in Pilsen, Czechoslovakia.
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MeSH Terms
Cartilage / metabolism,  pathology*
Collagen / metabolism*
Extracellular Matrix / metabolism,  ultrastructure
Hyalin / metabolism*
Lymph Nodes*
Microscopy, Electron
Soft Tissue Neoplasms / metabolism*,  ultrastructure
Reg. No./Substance:

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