| Cold agglutinins in infectious mononucleosis and heterophil-antibody-negative mononucleosis-like syndromes. | |
| | |
MedLine Citation:
|
PMID: 194643 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Cold agglutinins (CA) were evaluated prospectively in patients with various mononucleosis syndromes and in a large control group. Cold agglutinins with anti-i specificity were seen mainly in heterophil-positive or -negative Epstein-Barr virus (EBV)-induced infectious mononucleosis (31.8% of cases). Unclassified CA with equal reactivity against cord and adult erythrocytes were seen in 56 of 150 (37.3%) cases of heterophil-antibody-positive infectious mononucleosis (IM), in 1 of 7 (14.3%) cases of heterophil-negative EBV-induced IM, and in 12 of 31 (38.7%) cases of the heterophil-negative mononucleosis-like syndrome due to cytomegalovirus or other unspecified agents. One patient with heterophil-positive IM had a persistent, partially papain sensitive CA with anti-Pr-like activity. Anti-i CA were seen in less than 1.0% of healthy young adults (500) or patients without mononucleosis (500) submitted for heterophil studies. Unclassified CA were noted in 3.2% of the latter 1000 samples. |
| | |
Authors:
|
C A Horwitz; J Moulds; W Henle; G Henle; H Polesky; H H Balfour; B Schwartz; T Hoff |
Related Documents
:
|
21769233 - Graham-little piccardi lassueur syndrome: an unusual variant of follicular lichen planus. 3798083 - Cerebellar ataxia in infectious mononucleosis. 18230893 - Genetic obesity syndromes. |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Blood Volume: 50 ISSN: 0006-4971 ISO Abbreviation: Blood Publication Date: 1977 Aug |
Date Detail:
|
Created Date: 1977-09-02 Completed Date: 1977-09-02 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 7603509 Medline TA: Blood Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 195-202 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Agglutinins
/
analysis* Antibodies, Heterophile Antibodies, Viral / analysis Autoantibodies / analysis* Cold Temperature Cytomegalovirus / isolation & purification Herpesvirus 4, Human / isolation & purification Humans I Blood-Group System Immunoglobulin G / analysis Immunoglobulin M / analysis Infectious Mononucleosis / immunology*, microbiology Papain |
| Chemical | |
Reg. No./Substance:
|
0/Agglutinins; 0/Antibodies, Heterophile; 0/Antibodies, Viral; 0/Autoantibodies; 0/I Blood-Group System; 0/Immunoglobulin G; 0/Immunoglobulin M; EC 3.4.22.2/Papain |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Metabolic activity of phagocytosing granulocytes in chronic granulocytic leukemia: ultrastructural o...
Next Document: Induction of human granulocyte differentiation in vitro by ubiquitin and thymopoietin.