Document Detail

Cold agglutinin induced hemolysis in a newly diagnosed systemic lupus erythematosus.
MedLine Citation:
PMID:  20220336     Owner:  NLM     Status:  MEDLINE    
Systemic lupus erythematosus (SLE) is a well-known autoimmune chronic inflammatory disease, which can virtually affect any organ system in the body. Although hemolytic anemia has been known to occur in <10% of SLE patients, they are usually mediated through warm antibodies. It is extremely rare to see cold antibody-mediated hemolytic anemia in SLE, and only few cases have been reported in literature to our knowledge. This is a unique case report of SLE associated with cold agglutinin hemolytic anemia in a patient presented with generalized tender lymphadenopathy and typical B-symptoms including fever, night sweats, and significant weight loss.
Nandakumar Srinivasan; Alok Oswal; Sindhu Garg; Julie Nahar; Albina Gosmonova; Roopesh Nahar
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The American journal of the medical sciences     Volume:  339     ISSN:  1538-2990     ISO Abbreviation:  Am. J. Med. Sci.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-11     Completed Date:  2010-04-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370506     Medline TA:  Am J Med Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  270-3     Citation Subset:  AIM; IM    
Oklahoma University of Health Sciences Center, Oklahoma City, Oklahoma 73104, USA.
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MeSH Terms
Anemia, Hemolytic, Autoimmune / diagnosis,  etiology*
Cryoglobulins / adverse effects
Lupus Erythematosus, Systemic / diagnosis*,  therapy*
Reg. No./Substance:
0/Cryoglobulins; 0/cold agglutinins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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