Document Detail

Col2-GFP reporter mouse--a new tool to study skeletal development.
MedLine Citation:
PMID:  11891675     Owner:  NLM     Status:  MEDLINE    
Transgenic mice were generated that harbor a Col2-GFP reporter that marks chondrocytes and their immediate precursors during skeletal development. Cells engaged in chondrogenesis were identified by conventional fluorescence microscopy and confocal optical sectioning within their native environments in live embryos and in thick tissue slices. The use of these mice offers a novel approach for studying the role of chondrocytes in skeletal development.
J Y Cho; T D Grant; G P Lunstrum; W A Horton
Related Documents :
10556625 - Targeted disruption of the gene encoding the proteolipid subunit of mouse vacuolar h(+)...
11586245 - Angiotensin type ii receptor expression and ureteral budding.
24660605 - Curative effect of xuebijing injection on severe pulmonary contusion.
9133445 - Smad5 induces ventral fates in xenopus embryo.
15003795 - Metabolic activity of osteoblasts retrieved from osteoarthritic patients after stimulat...
1738215 - Protein malnutrition alone and in combination with endotoxin impairs systemic and gut-a...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of medical genetics     Volume:  106     ISSN:  0148-7299     ISO Abbreviation:  Am. J. Med. Genet.     Publication Date:  2001  
Date Detail:
Created Date:  2002-03-13     Completed Date:  2002-06-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7708900     Medline TA:  Am J Med Genet     Country:  United States    
Other Details:
Languages:  eng     Pagination:  251-3     Citation Subset:  IM    
Research Center, Shriners Hospital for Children, Portland, OR 97201, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Bone Development*
Chondrocytes / physiology
Collagen Type II / genetics*,  physiology
Disease Models, Animal*
Genes, Reporter / physiology
Green Fluorescent Proteins
Luminescent Proteins / genetics*,  physiology
Mice, Transgenic
Organ Specificity / physiology
Reg. No./Substance:
0/Collagen Type II; 0/Luminescent Proteins; 147336-22-9/Green Fluorescent Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Pseudoachondroplasia and multiple epiphyseal dysplasia: New etiologic developments.
Next Document:  Dyssegmental dysplasia, Silverman-Handmaker type: unexpected role of perlecan in cartilage developme...