Document Detail


Coincidence of immune thrombocytopenia, intracranial hemorrhage and graft-versus-host disease in an 11-year-old girl.
MedLine Citation:
PMID:  20830662     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Primary immune thrombocytopenia (ITP) in children is usually self-limiting and harmless but can, rarely, result in life-threatening complications. The case of an 11-year-old girl with ITP is presented who developed recurrent intracranial hemorrhages followed by cerebral infarctions. The clinical course was complicated by a graft-versus-host disease involving several organs. Treatment was performed according to the current international consensus report of 2010 with glucocorticoids, immunoglobulin G, anti-D-immunoglobulin and additionally embolisation of the splenic artery. The girl survived. Reliable predictors, preventive measures for life-threatening complications in ITP and more information about the effectiveness and side-effects of the recommended treatment are urgently needed.
Authors:
M Landgraf; M Siekmeyer; L Fischer; U Bierbach; W Siekmeyer; J Meixensberger; W Hirsch; W Kiess
Publication Detail:
Type:  Journal Article     Date:  2010-09-09
Journal Detail:
Title:  Klinische Pädiatrie     Volume:  222     ISSN:  1439-3824     ISO Abbreviation:  Klin Padiatr     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0326144     Medline TA:  Klin Padiatr     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  378-82     Citation Subset:  IM    
Copyright Information:
© Georg Thieme Verlag KG Stuttgart · New York.
Affiliation:
Zentrum für Frauen- und Kindermedizin, Universität Leipzig, Liebigstrasse 20a, Leipzig, Germany. mirjam.landgraf@medizin.uni-leipzig.de
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Comment In:
Klin Padiatr. 2010 Nov;222(6):337-9   [PMID:  21058220 ]

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