| Coincidence of immune thrombocytopenia, intracranial hemorrhage and graft-versus-host disease in an 11-year-old girl. | |
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MedLine Citation:
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PMID: 20830662 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Primary immune thrombocytopenia (ITP) in children is usually self-limiting and harmless but can, rarely, result in life-threatening complications. The case of an 11-year-old girl with ITP is presented who developed recurrent intracranial hemorrhages followed by cerebral infarctions. The clinical course was complicated by a graft-versus-host disease involving several organs. Treatment was performed according to the current international consensus report of 2010 with glucocorticoids, immunoglobulin G, anti-D-immunoglobulin and additionally embolisation of the splenic artery. The girl survived. Reliable predictors, preventive measures for life-threatening complications in ITP and more information about the effectiveness and side-effects of the recommended treatment are urgently needed. |
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Authors:
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M Landgraf; M Siekmeyer; L Fischer; U Bierbach; W Siekmeyer; J Meixensberger; W Hirsch; W Kiess |
Publication Detail:
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Type: Journal Article Date: 2010-09-09 |
Journal Detail:
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Title: Klinische Pädiatrie Volume: 222 ISSN: 1439-3824 ISO Abbreviation: Klin Padiatr Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-11-08 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0326144 Medline TA: Klin Padiatr Country: Germany |
Other Details:
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Languages: eng Pagination: 378-82 Citation Subset: IM |
Copyright Information:
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© Georg Thieme Verlag KG Stuttgart · New York. |
Affiliation:
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Zentrum für Frauen- und Kindermedizin, Universität Leipzig, Liebigstrasse 20a, Leipzig, Germany. mirjam.landgraf@medizin.uni-leipzig.de |
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| Comments/Corrections | |
Comment In:
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Klin Padiatr. 2010 Nov;222(6):337-9
[PMID:
21058220
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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