Document Detail


Cohorts and consortia conference: a summary report (Banff, Canada, June 17-19, 2009).
MedLine Citation:
PMID:  21203821     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Epidemiologic studies have adapted to the genomics era by forming large international consortia to overcome issues of large data volume and small sample size. Whereas both cohort and well-conducted case-control studies can inform disease risk from genetic susceptibility, cohort studies offer the additional advantages of assessing lifestyle and environmental exposure-disease time sequences often over a life course. Consortium involvement poses several logistical and ethical issues to investigators, some of which are unique to cohort studies, including the challenge to harmonize prospectively collected lifestyle and environmental exposures validly across individual studies. An open forum to discuss the opportunities and challenges of large-scale cohorts and their consortia was held in June 2009 in Banff, Canada, and is summarized in this report.
Authors:
Paolo Boffetta; Graham A Colditz; John D Potter; Laurence Kolonel; Paula J Robson; Reza Malekzadeh; Daniela Seminara; Ellen L Goode; Keun-Young Yoo; Paul Demers; Richard Gallagher; Ross Prentice; Yutaka Yasui; Kieran O'Doherty; Gloria M Petersen; Cornelia M Ulrich; Ilona Csizmadi; Ernest K Amankwah; Nigel T Brockton; Karen Kopciuk; S Elizabeth McGregor; Linda E Kelemen
Publication Detail:
Type:  Comparative Study; Congresses; Research Support, Non-U.S. Gov't     Date:  2011-01-04
Journal Detail:
Title:  Cancer causes & control : CCC     Volume:  22     ISSN:  1573-7225     ISO Abbreviation:  Cancer Causes Control     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-21     Completed Date:  2011-06-02     Revised Date:  2011-06-07    
Medline Journal Info:
Nlm Unique ID:  9100846     Medline TA:  Cancer Causes Control     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  463-8     Citation Subset:  IM    
Affiliation:
The Tisch Cancer Institute, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029, USA. paolo.boffetta@i-pri.org
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MeSH Terms
Descriptor/Qualifier:
Canada
Case-Control Studies*
Clinical Trials as Topic / methods
Cohort Studies*
Environmental Exposure / analysis
Humans
Research Report*
Risk Assessment / methods
Sample Size
Grant Support
ID/Acronym/Agency:
R01 CA122443-05/CA/NCI NIH HHS; //Canadian Institutes of Health Research

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